Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q99MU3 | - |
- |
General Information | Comment | Organism |
---|---|---|
malfunction | ADAR1-/- homozygous embryos die at E11.0 to E12.5. Widespread apoptosis is detected in many tissues of ADAR1-/- embryos collected live at E10.5 to E11.5, despite their normal gross appearance | Mus musculus |
physiological function | ADAR1 is required for cell survival and embryo development by protecting against stress-induced apoptosis | Mus musculus |