General Stability | Organism |
---|---|
unstable to freezing and thawing | Streptomyces albus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 1 mM, 45% loss of activity. 1 mM, 91% loss of activity | Streptomyces albus | |
Deoxycoformycin | - |
Streptomyces albus | |
additional information | not inhibited by metal chelators, iodoacetamide and NEM | Streptomyces albus | |
PCMB | 0.1 mM, 40% loss of activity | Streptomyces albus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.5 | - |
S-adenosyl-L-homocysteine | - |
Streptomyces albus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
56100 | - |
1 * 56100, SDS-PAGE | Streptomyces albus |
58300 | - |
sucrose density gradient centrifugation | Streptomyces albus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-homocysteine + H2O | Streptomyces albus | major route of S-adenosylhomocysteine metabolism | adenosine + L-homocysteine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces albus | - |
ATCC 13257 | - |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces albus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
15.4 | - |
- |
Streptomyces albus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-homocysteine + H2O | - |
Streptomyces albus | adenosine + L-homocysteine | - |
? | |
S-adenosyl-L-homocysteine + H2O | major route of S-adenosylhomocysteine metabolism | Streptomyces albus | adenosine + L-homocysteine | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 56100, SDS-PAGE | Streptomyces albus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Streptomyces albus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
stable at room temperature in presence of 1 mM DTT | Streptomyces albus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
26 | - |
S-adenosyl-L-homocysteine | - |
Streptomyces albus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Streptomyces albus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7.5 | more than 90% of activity maximum at pH 6.5 and 7.5, rapid drop of activity below pH 6.0 and above 9.0 | Streptomyces albus |