Literature summary for 3.5.4.10 extracted from

Bulock, K.G.; Beardsley, G.P.; Anderson, K.S.
The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase): A surprising lack of substrate channeling (2002), J. Biol. Chem., 277, 22168-22174.

Search for more literature for 3.5.4.10

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0014	-	5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide	pH 7.4	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	bifunctional enzyme 5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase	-

Reaction

Reaction	Comment	Organism	Reaction ID
IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	mechanism,kinetics, enzyme reaction draws the overall bifunctional reaction towards the IMP product	Homo sapiens	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide	-	Homo sapiens	IMP + H2O	-	ir

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)