Crystallization (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-hydroxypyrimidine | binding structure modeling, inhibition mechanism, acts as a transition state analogue | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | 1 metal ion is tightly bound to the active site, binding structure modeling, Fourier mapping | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | Q12178 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
cytosine + H2O = uracil + NH3 | active site architecture and substrate binding, catalytic mechanism | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-fluorocytosine + H2O | - |
Saccharomyces cerevisiae | 5-fluorouracil + NH3 | - |
? | |
5-methylcytosine + H2O | - |
Saccharomyces cerevisiae | thymine + NH3 | - |
? | |
cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | a monomer is a three-layered alpha/beta/alpha structure with a central beta sheet sandwiched on either side by alpha-helices | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
CD | - |
Saccharomyces cerevisiae |