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Literature summary for 3.5.3.16 extracted from

  • Nakajima, M.; Shirokane, Y.; Mizusawa, K.
    A new amidinohydrolase, methylguanidine amidinohydrolase from Alcaligenes sp. N-42 (1980), FEBS Lett., 110, 43-46.
    View publication on PubMed
Search for more literature for 3.5.3.16

Application

Application Comment Organism
medicine useful as a means of detoxication and/or assay of methylguanidine in body fluids Alcaligenes sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methylguanidine + H2O Alcaligenes sp.
-
 methylamine + urea
-
 ?
methylguanidine + H2O Alcaligenes sp. N-42
-
 methylamine + urea
-
 ?

Organism

Organism UniProt Comment Textmining
Alcaligenes sp.
-
 N-42
-
Alcaligenes sp. N-42
-
 N-42
-

Purification (Commentary)

Purification (Comment) Organism
-
 Alcaligenes sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
102
-
-
 Alcaligenes sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
agmatine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. ?
-
 ?
ethylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. ethylamine + urea
-
 ?
ethylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. N-42 ethylamine + urea
-
 ?
guanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. NH3 + urea
-
 ?
methylguanidine + H2O
-
 Alcaligenes sp. methylamine + urea
-
 ?
methylguanidine + H2O
-
 Alcaligenes sp. N-42 methylamine + urea
-
 ?
additional information no hydrolysis of guanidino compounds with carboxyl group Alcaligenes sp. ?
-
 ?
additional information no hydrolysis of guanidino compounds with carboxyl group Alcaligenes sp. N-42 ?
-
 ?
n-butylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. n-butylamine + urea
-
 ?
n-butylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. N-42 n-butylamine + urea
-
 ?
n-propylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. n-propylamine + urea
-
 ?
n-propylguanidine + H2O slight hydrolysis, 1.3% of the natural substrate methylguanidine Alcaligenes sp. N-42 n-propylamine + urea
-
 ?