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Literature summary for 3.5.3.15 extracted from

  • Ishigami, A.; Ohsawa, T.; Hiratsuka, M.; Taguchi, H.; Kobayashi, S.; Saito, Y.; Murayama, S.; Asaga, H.; Toda, T.; Kimura, N.; Maruyama, N.
    Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease (2005), J. Neurosci. Res., 80, 120-128.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of patients with Alzheimer's disease, strongly suggests that peptidylarginine deiminase has an important role in the onset and progression of abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of Alzheimer's disease ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with Alzheimer's disease
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
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Homo sapiens
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brain abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of patients with Alzheimer's disease Homo sapiens
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hippocampus abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of patients with Alzheimer's disease Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of patients with Alzheimer's disease, strongly suggests that peptidylarginine deiminase has an important role in the onset and progression of abnormal accumulation of citrullinated proteins and abnormal activation of PAD2 in hippocampi of Alzheimer's disease Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
PAD2
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Homo sapiens