Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | enhances activity, maximal activation at 2 mM | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
monoiodoacetate | - |
Rattus norvegicus | |
PCMB | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required | Rattus norvegicus | |
Ca2+ | maximal activity in presence of 8-10 mM CaCl2 | Rattus norvegicus | |
Ca2+ | 10 mM, 11% of the activity with Ca2+ | Rattus norvegicus | |
Sr2+ | 10 mM, 85% of the activity with Ca2+ | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
48000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein L-Arg + H2O | Rattus norvegicus | citrullyl residues in the membranous protein of horny cells of the epidermis of newborn rat are formed by the action of epidermal peptidylarginine deiminase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00077 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-Gly-L-Arg + H2O | - |
Rattus norvegicus | benzoyl-Gly-L-citrulline + NH3 | - |
ir | |
benzoyl-L-Arg + H2O | - |
Rattus norvegicus | benzoyl-L-citrulline + NH3 | - |
ir | |
benzoyl-L-Arg-NH2 + H2O | - |
Rattus norvegicus | benzoyl-L-citrullineamide + NH3 | - |
ir | |
L-Arg + H2O | negligible action | Rattus norvegicus | L-citrulline + NH3 | - |
? | |
protein L-Arg + H2O | citrullyl residues in the membranous protein of horny cells of the epidermis of newborn rat are formed by the action of epidermal peptidylarginine deiminase | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
- |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Rattus norvegicus |