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Literature summary for 3.5.3.1 extracted from

  • Bratt, J.M.; Franzi, L.M.; Linderholm, A.L.; Last, M.S.; Kenyon, N.J.; Last, J.A.
    Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin (2009), Toxicol. Appl. Pharmacol., 234, 273-280.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.3.1

Inhibitors

Inhibitors Comment Organism Structure
additional information testing consequences of inhibiting arginase activity in vivo with NO production, lung inflammation, and lung function in both C57BL/6 and NOS2 knockout mice undergoing ovalbumin-induced airway inflammation, a mouse model of asthma Mus musculus
nor-NOHA competitive inhibitor of both isoforms of arginase Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 normal and nitric oxide synthase 2-knockout mice
-

Source Tissue

Source Tissue Comment Organism Textmining
lung airways Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Mus musculus L-ornithine + urea
-
 ?

Synonyms

Synonyms Comment Organism
arginase
-
 Mus musculus
arginase I
-
 Mus musculus
arginase II
-
 Mus musculus