Literature summary for 3.5.3.1 extracted from

Sosroseno, W.; Musa, M.; Ravichandran, M.; Fikri Ibrahim, M.; Bird, P.S.; Seymour, G.J.
Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans (2006), Oral Microbiol. Immunol., 21, 145-150.

Search for more literature for 3.5.3.1

Activating Compound

Activating Compound	Comment	Organism	Structure
dexamethasone	augments arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells	Mus musculus
interleukin-4	augments arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells	Mus musculus
lipopolysaccharide	lipopolysaccharide from Actinobacillus actinomycetemcomitans or Escherichia coli	Mus musculus
additional information	interferon-gamma does not augment arginase activity in Actinobacillus actinomycetemcomitans lipopolysaccharide-stimulated cells	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
L-norvaline	blocks arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells	Mus musculus
additional information	cell treatment with anti-CD14 and anti-toll-like receptor 4 but not anti-toll-like receptor 2 antibody decreases arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells; DL-norvaline does not block arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells	Mus musculus
Polymyxin B	blocks arginase activity in Actinobacillus actinomycetemcomitans-lipopolysaccharide-stimulated cells	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-arginine + H2O	Mus musculus	-	L-ornithine + urea	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
macrophage	-	Mus musculus	-
RAW264.7 cell	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arginine + H2O	-	Mus musculus	L-ornithine + urea	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)