Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
sitting drop vapour diffusion method with 0.1 M Bis-Tris-HCl (pH 5.5), 10-20% (w/v) PEG-3350 | Homo sapiens |
General Stability | Organism |
---|---|
perdeuterated human arginase I exhibits catalytic activity essentially identical to that of the unlabeled enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2(S)-amino-6-boronohexanoic acid | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.6 | - |
L-arginine | at pH 8.5, in H2O buffer | Homo sapiens | |
7.7 | - |
L-arginine | at pH 8.5, in D2O buffer | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | manganese metalloenzyme, each monomer contains two manganese ions | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34740 | - |
theoretical value for unlabeled arginase I | Homo sapiens |
37030 | - |
perdeuterated protein, estimated from amino acid sequence | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | Homo sapiens | - |
L-ornithine + urea | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P05089 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | - |
Homo sapiens | L-ornithine + urea | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | x-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
arginase I | - |
Homo sapiens |