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Literature summary for 3.5.3.1 extracted from

  • Xie, X.; Li, X.; Wang, Z.; Wang, C.
    Thermokinetic studies on the activation of bovine liver arginase by manganese ions (2004), Thermochim. Acta, 414, 19-23.
No PubMed abstract available
Search for more literature for 3.5.3.1

Inhibitors

Inhibitors Comment Organism Structure
L-lysine
-
 Bos taurus
L-ornithine product inhibition Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ maximum activity at 0.1 mM, presence of Mn2+ results in increase in Vmax, and a higher sensitivity to product and L-lysine inhibition, with no change in KM-value for L-arginine Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Bos taurus L-ornithine + urea
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.4
-
-
 Bos taurus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.7
-
 L-ornithine presence of 0.1 mM Mn2+, pH 9.4, 37°C Bos taurus
1.18
-
 L-ornithine pH 9.4, 37°C Bos taurus
3.1
-
 L-lysine presence of 0.1 mM Mn2+, pH 9.4, 37°C Bos taurus
5.6
-
 L-lysine pH 9.4, 37°C Bos taurus