Literature summary for 3.5.3.1 extracted from

Hirata, M.; Obayashi, S.; Sakamoto, S.; Aso, T.; Imamura, M.; Azuma, H.
Involvement of arginase in regulating myometrial contractions during gestation in the rat (2006), Mol. Hum. Reprod., 12, 513-518.

Search for more literature for 3.5.3.1

Application

Application	Comment	Organism
medicine	significant decrease of enzyme activity during 7th-21st day of gestation, significant increase in enzyme activity at term gestation, day 22. Gestational changes in enzyme activity negatively correlate with those in cyclic GMP production and positively correlate with those in endogenous NO synthase inhibitors and endothelin-1 contents. Enhanced enzyme activity at term gestation may be implicated in increasing myometrial contractions mediated by increase in endothelin-1	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
myometrium	significant decrease of enzyme activity during 7th-21st day of gestation, significant increase in enzyme activity at term gestation, day 22. Gestational changes in enzyme activity negatively correlate with those in cyclic GMP production and positively correlate with those in endogenous NO synthase inhibitors and endothelin-1 contents. Enhanced enzyme activity at term gestation may be implicated in increasing myometrial contractions mediated by increase in endothelin-1	Rattus norvegicus	-

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Release 2023.1 (January 2023)