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Literature summary for 3.5.3.1 extracted from

  • Tormanen, C.D.
    Inhibition of rat liver and kidney arginase by cadmium ion (2006), J. Enzyme Inhib. Med. Chem., 21, 119-123.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cd2+ mixed competitive inhibitor. Kidney enzyme is more sensitive to inhibition than liver enzyme. Cd2+ enhances substrate activation of kidney enzyme while still being inhibitory. Cd2+ is also inhibitory to kidney enzyme in presence of Mn2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-