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Literature summary for 3.5.3.1 extracted from

  • Roberts, S.C.; Tancer, M.J.; Polinsky, M.R.; Gibson, K.M.; Heby, O.; Ullman, B.
    Arginase plays a pivotal role in polyamine precursor metabolism in Leishmania. Characterization of gene deletion mutants (2004), J. Biol. Chem., 279, 23668-23678.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information enzyme deletion mutant, parasites express no enzymic activity, lack an intracellular ornithine pool, and are auxotrophic for ornithine or polyamines. Expression of a mutant enzyme lacking the glycosomal targeting sequence leads to an enzyme mislocalized to the cytosol and there restoring the polyamine auxotrophy of the deletion mutant Leishmania mexicana

Localization

Localization Comment Organism GeneOntology No. Textmining
glycosome
-
Leishmania mexicana 20015
-

Organism

Organism UniProt Comment Textmining
Leishmania mexicana
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification enzyme sequence contains a glycosomal targeting signal Leishmania mexicana

Synonyms

Synonyms Comment Organism
ARG
-
Leishmania mexicana