General Stability | Organism |
---|---|
unstable in absence of 5-oxo-L-proline | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
ATP | without 5-oxoproline | Rattus norvegicus | |
0.16 | - |
5-oxoproline | initial Km in presence of GTP | Rattus norvegicus | |
0.17 | - |
UTP | without 5-oxoproline | Rattus norvegicus | |
0.17 | - |
ITP | without 5-oxoproline | Rattus norvegicus | |
0.18 | - |
5-oxoproline | initial Km in presence of ITP | Rattus norvegicus | |
0.2 | - |
5-oxoproline | initial Km in presence of UTP | Rattus norvegicus | |
0.41 | - |
5-oxoproline | in presence of ATP | Rattus norvegicus | |
0.41 | - |
ITP | 5-oxoproline added | Rattus norvegicus | |
0.42 | - |
ATP | 5-oxoproline added | Rattus norvegicus | |
0.5 | - |
5-oxoproline | final Km in presence of UTP | Rattus norvegicus | |
0.57 | - |
5-oxoproline | final Km in presence of GTP | Rattus norvegicus | |
0.58 | - |
5-oxoproline | final Km in presence of ITP | Rattus norvegicus | |
1.11 | - |
UTP | 5-oxoproline added | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-oxo-L-proline + H2O + ATP | Rattus norvegicus | - |
L-glutamate + ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-imidazolidone-4-carboxylate + ATP + H2O | promotes enzymatic hydrolysis of ATP but is not itself hydrolyzed | Rattus norvegicus | 2-imidazolidone + ADP + phosphate | - |
? | |
2-piperidone-6-carboxylate + ATP + H2O | - |
Rattus norvegicus | 2-aminoadipate + phosphate + ADP | - |
? | |
3-methyl-5-oxoproline + H2O | - |
Rattus norvegicus | 2-amino-3-methylpentanedioic acid | - |
? | |
4-methyl-5-oxoproline + H2O | - |
Rattus norvegicus | 2-amino-4-methylpentanedioic acid | - |
? | |
5-oxo-L-proline + H2O + ATP | - |
Rattus norvegicus | L-glutamate + ADP + phosphate | - |
? | |
ATP + H2O | - |
Rattus norvegicus | ? | - |
? | |
GTP + H2O | - |
Rattus norvegicus | ? | - |
? | |
ITP + H2O | - |
Rattus norvegicus | ? | - |
? | |
additional information | 5-oxo-D-proline, 2-pyrrolidone-4-carboxylate, N-methyl-5-oxo-L-proline and N-acetyl-L-alanine are no substrates | Rattus norvegicus | ? | - |
? | |
UTP + H2O | - |
Rattus norvegicus | ? | - |
? |