Literature summary for 3.5.2.9 extracted from

Hsu, T.; Meister, A.
Metabolism in vivo of 5-oxo-L-proline and its inhibition by analogs of 5-oxo-L-proline (1985), Methods Enzymol., 113, 468-471.

Search for more literature for 3.5.2.9

Inhibitors

Inhibitors	Comment	Organism	Structure
3-methyl-5-oxo-L-proline	-	Mus musculus
L-2-imidazolidone-4-carboxylate	-	Mus musculus
L-2-imidazolidone-4-carboxylate	-	Rattus norvegicus
L-2-Oxothiazolidine-4-carboxylate	competitive inhibitor	Mus musculus
L-2-Oxothiazolidine-4-carboxylate	-	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5-oxo-L-proline + H2O + ATP	Mus musculus	-	L-glutamate + ADP + phosphate	-	?
5-oxo-L-proline + H2O + ATP	Rattus norvegicus	-	L-glutamate + ADP + phosphate	-	?
5-oxo-L-proline + H2O + ATP	Mus musculus NCS	-	L-glutamate + ADP + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	mouse, NCS strain	-
Mus musculus NCS	-	mouse, NCS strain	-
Rattus norvegicus	-	rat	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney	-	Mus musculus	-
kidney	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-oxo-L-proline + H2O + ATP	-	Mus musculus	L-glutamate + ADP + phosphate	-	?
5-oxo-L-proline + H2O + ATP	-	Rattus norvegicus	L-glutamate + ADP + phosphate	-	?
5-oxo-L-proline + H2O + ATP	-	Mus musculus NCS	L-glutamate + ADP + phosphate	-	?
L-2-oxothiazolidine-4-carboxylate + H2O + ATP	-	Rattus norvegicus	L-cysteine + ADP + phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)