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Literature summary for 3.5.2.5 extracted from

  • Nourimand, M.; Todd, C.D.
    Allantoin contributes to the stress response in cadmium-treated Arabidopsis roots (2017), Plant Physiol. Biochem., 119, 103-109 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene ALN, quantitative RT-PCR enzyme expression analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information downregulation of ALN and UO (uricase) genes impairing allantoin accumulation in Cd-treated Col-0 roots. In enzyme-deficient aln-3 roots, allantoin content increases nearly 2fold at 1 mM CdCl2 but is similar to untreated roots at 1.5 mM CdCl2. T-DNA insertions in allantoinase cause the constitutive accumulation of allantoin resulting in plant resistance to different abiotic stresses such as drought, salinity (NaCl), and heavy metal cadmium toxicity Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q94AP0
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Arabidopsis thaliana Col-0 Q94AP0
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-

Source Tissue

Source Tissue Comment Organism Textmining
root
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Arabidopsis thaliana
-

Synonyms

Synonyms Comment Organism
ALN
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Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction T-DNA insertions in allantoinase cause the constitutive accumulation of allantoin resulting in plant resistance to different abiotic stresses such as drought, salinity (NaCl), and heavy metal cadmium toxicity. High concentration of allantoin in allantoinase-negative mutant (aln-3) leaves alleviates cadmium toxicity via inducing antioxidant mechanisms in these plants. In contrast with wild-type leaves, high levels of Cd in Col-0 roots reduces transcript abundance of uricase, leading to a significant decline in allantoin level of treated roots at 1000 and 1500 mM CdCl2, molecular mechanism underlying allantoin content of root in response to Cd stress, overview. Root elongation is reduced in Cd-treated wild-type but not enzyme-deficient plants. Despite higher Cd content, aln-3 roots contain lower reactive oxygen species concentrations. Antioxidant enzymes are more active in aln-3 roots following Cd treatment Arabidopsis thaliana
metabolism Cd tolerance and the role allantoin plays in plant abiotic stress response are linked Arabidopsis thaliana