Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-carbamoyl[1,1'-biphenyl]-3-yl cyclohexylcarbamate | - |
Rattus norvegicus | |
phenyl 4-[(1H-indol-1-yl)methyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(4-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(5-chloro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(5-cyano-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(5-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(5-methoxy-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(5-methyl-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(6-fluoro-1H-indol-1-yl)ethyl]piperazine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(6-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(7-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[2-(9H-carbazol-9-yl)ethyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[3-(1H-indol-1-yl)propyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl 4-[4-(1H-indol-1-yl)butyl]piperidine-1-carboxylate | - |
Rattus norvegicus | |
phenyl [4-(1H-indol-1-yl)butyl]carbamate | - |
Rattus norvegicus | |
phenyl [5-(1H-indol-1-yl)pentyl]carbamate | - |
Rattus norvegicus | |
phenyl [6-(1H-indol-1-yl)hexyl]carbamate | - |
Rattus norvegicus | |
phenyl [7-(1H-indol-1-yl)heptyl]carbamate | - |
Rattus norvegicus | |
phenyl [8-(1H-indol-1-yl)octyl]carbamate | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P97612 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000046 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(6-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.000052 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(7-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00006 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | 3'-carbamoyl[1,1'-biphenyl]-3-yl cyclohexylcarbamate | |
0.000093 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl [7-(1H-indol-1-yl)heptyl]carbamate | |
0.000094 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl [5-(1H-indol-1-yl)pentyl]carbamate | |
0.00011 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00011 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(4-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00013 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(5-fluoro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00018 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[4-(1H-indol-1-yl)butyl]piperidine-1-carboxylate | |
0.00024 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl [8-(1H-indol-1-yl)octyl]carbamate | |
0.00025 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl [6-(1H-indol-1-yl)hexyl]carbamate | |
0.00036 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(5-methoxy-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00041 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(5-chloro-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00041 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(9H-carbazol-9-yl)ethyl]piperidine-1-carboxylate | |
0.00057 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[3-(1H-indol-1-yl)propyl]piperidine-1-carboxylate | |
0.00074 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(5-methyl-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00081 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(6-fluoro-1H-indol-1-yl)ethyl]piperazine-1-carboxylate | |
0.00096 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl [4-(1H-indol-1-yl)butyl]carbamate | |
0.00097 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[2-(5-cyano-1H-indol-1-yl)ethyl]piperidine-1-carboxylate | |
0.00987 | - |
37°C, pH 7.4, assay in brain microsomes, substrate N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide | Rattus norvegicus | phenyl 4-[(1H-indol-1-yl)methyl]piperidine-1-carboxylate |