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Literature summary for 3.5.1.99 extracted from

  • Quistad, G.B.; Klintenberg, R.; Caboni, P.; Liang, S.N.; Casida, J.E.
    Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice (2006), Toxicol. Appl. Pharmacol., 211, 78-83.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
benzol
-
Mus musculus
chlorpyrifos oxon
-
Mus musculus
decyl benzodioxaphosphorin oxide
-
Mus musculus
diazoxon
-
Mus musculus
dichlorvos
-
Mus musculus
diisopropyl fluorophosphate
-
Mus musculus
dodecyl benzodioxaphosphorin oxide
-
Mus musculus
dodecyl sulfonyl fluoride
-
Mus musculus
ethyl octylphosphonofluoridate
-
Mus musculus
heptyl benzodioxaphosphorin oxide
-
Mus musculus
isopropyl dodecylfluorophosphate
-
Mus musculus
methyl arachidonylfluoroposphate
-
Mus musculus
methyl octylphosphonofluoridate
-
Mus musculus
N-n-heptyl benzodioxaphosphorin oxide
-
Mus musculus
O-n-octyl benzodioxaphosphorin oxide
-
Mus musculus
octyl sulfonyl fluoride
-
Mus musculus
paraoxon
-
Mus musculus
S-heptyl benzodioxaphosphorin oxide
-
Mus musculus
S-nonyl benzodioxaphosphorin oxide
-
Mus musculus
S-pentyl benzodioxaphosphorin oxide
-
Mus musculus
stearyl benzodioxaphosphorin oxide
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
Male albino Swiss–Webster
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
anandamide + H2O
-
Mus musculus ethanolamine + arachidonic acid
-
?

Synonyms

Synonyms Comment Organism
FAAH
-
Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000001
-
-
Mus musculus methyl arachidonylfluoroposphate
0.00000015
-
-
Mus musculus S-nonyl benzodioxaphosphorin oxide
0.0000005
-
-
Mus musculus dodecyl benzodioxaphosphorin oxide
0.0000006
-
-
Mus musculus ethyl octylphosphonofluoridate
0.00000079
-
-
Mus musculus methyl octylphosphonofluoridate
0.0000012
-
-
Mus musculus decyl benzodioxaphosphorin oxide
0.0000017
-
-
Mus musculus S-heptyl benzodioxaphosphorin oxide
0.000002
-
-
Mus musculus isopropyl dodecylfluorophosphate
0.000002
-
-
Mus musculus dodecyl sulfonyl fluoride
0.0000057
-
-
Mus musculus S-pentyl benzodioxaphosphorin oxide
0.000019
-
-
Mus musculus octyl sulfonyl fluoride
0.00004
-
-
Mus musculus chlorpyrifos oxon
0.000064
-
-
Mus musculus N-n-heptyl benzodioxaphosphorin oxide
0.000073
-
-
Mus musculus O-n-octyl benzodioxaphosphorin oxide
0.000126
-
-
Mus musculus heptyl benzodioxaphosphorin oxide
0.000131
-
-
Mus musculus stearyl benzodioxaphosphorin oxide
0.00054
-
-
Mus musculus paraoxon
0.0018
-
-
Mus musculus dichlorvos
0.009
-
-
Mus musculus diazoxon
0.011
-
-
Mus musculus benzol
0.048
-
-
Mus musculus diisopropyl fluorophosphate