Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one | - |
Rattus norvegicus | |
3'-carbamoyl-biphenyl-3-yl-cyclohexylcarbamate | - |
Rattus norvegicus | |
N-(4-hydroxy-2-methylphenyl) arachidonoyl amide | i.e. VDM11, inhibits the metabolism of anandamide by rat brain FAAH. Inhibition may at least in part be a consequence of the compound acting as an alternative substrate | Rattus norvegicus | |
N-(4-hydroxyphenyl)arachidonylamide | i.e. AM404, inhibits the metabolism of anandamide by rat brain FAAH | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
SpragueDawley | - |
Rattus norvegicus Sprague-Dawley | - |
SpragueDawley | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
anandamide + H2O | - |
Rattus norvegicus | ethanolamine + arachidonic acid | - |
? | |
N-(4-hydroxy-2-methylphenyl) arachidonoyl amide + H2O | the rate of metabolism of VDM11 is about 1520% of that for anandamide | Rattus norvegicus | 4-amino-m-cresol + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAAH | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0021 | - |
N-(4-hydroxyphenyl)arachidonylamide | in the presence of fatty acid-free bovine serum albumin (0.125% w/v). In the absence of fatty acid-free bovine serum albumin, the IC50 value is reduced | Rattus norvegicus | |
0.0026 | - |
N-(4-hydroxy-2-methylphenyl) arachidonoyl amide | in the presence of fatty acid-free bovine serum albumin (0.125% w/v). In the absence of fatty acid-free bovine serum albumin, the IC50 value is reduced | Rattus norvegicus |