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Literature summary for 3.5.1.98 extracted from

  • Hnisz, D.; Bardet, A.F.; Nobile, C.J.; Petryshyn, A.; Glaser, W.; Schoeck, U.; Stark, A.; Kuchler, K.
    A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis (2012), PLoS Genet., 8, e1003118.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.98

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus Set3C is a conserved nuclear complex, Set3 interacts with Hos2, immunohistochemic subcellular localization analysis, overview Candida albicans 5634
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Candida albicans deacetylation of histone H4 by Set3C is independent of H3K4 methylation at the PFK1 locus. Set3 interacts with Hos2 ?
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 ?
N-acetyl-lysine-histone H4 + H2O Candida albicans
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 acetate + histone H4
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 ?
N-acetyl-lysine4-histone H3 + H2O Candida albicans
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 acetate + histone H3
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 ?

Organism

Organism UniProt Comment Textmining
Candida albicans
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information deacetylation of histone H4 by Set3C is independent of H3K4 methylation at the PFK1 locus. Set3 interacts with Hos2 Candida albicans ?
-
 ?
N-acetyl-lysine-histone H4 + H2O
-
 Candida albicans acetate + histone H4
-
 ?
N-acetyl-lysine4-histone H3 + H2O
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 Candida albicans acetate + histone H3
-
 ?

Synonyms

Synonyms Comment Organism
Set3 complex
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 Candida albicans
Set3C
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 Candida albicans

General Information

General Information Comment Organism
evolution Set3C is a conserved nuclear complex, Set3 interacts with Hos2 Candida albicans
physiological function the Set3 complex acts as a repressor of hyphal differentiation and its function requires functional cAMP/PKA signaling, Set3C also controls morphogenesis through a transcription factor cluster, it is a co-factor of glycolysis and morphogenesis regulators, Set3C recruitment predicts induction and depletion predicts repression of yeast-to-hypha transition, molecular mechanism, overview. The Set3C decorates highly transcribed genes. The four phase-specific Set3C target transcription factors form a core transcriptional circuit Candida albicans