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Literature summary for 3.5.1.98 extracted from

  • Kaufmann, I.; White, E.; Azad, A.; Marguerat, S.; Baehler, J.; Proudfoot, N.J.
    Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase (2010), Mol. Cell. Biol., 30, 3396-3410.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
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Synonyms

Synonyms Comment Organism
Clr6
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Schizosaccharomyces pombe

General Information

General Information Comment Organism
physiological function role for Clr6 in transcriptional regulation of amino acid permease gene per1. When ammonia is used as the nitrogen source, low levels of per1 are transcribed and histones in the coding and surrounding regions of per1 are acetylated. In the presence of proline, histones at per1 are deacetylated in a Clr6-dependent manner Schizosaccharomyces pombe