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Literature summary for 3.5.1.98 extracted from
- Troglitazone inhibits histone deacetylase activity in breast cancer cells (2010), Cancer Lett., 288, 236-250.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| PXD101 | - |
Homo sapiens |  |
| sodium butyrate | - |
Homo sapiens | |
| trichostatin A | - |
Homo sapiens | |
| troglitazone | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast cancer cell | - |
Homo sapiens | - |
| MCF-7 cell | - |
Homo sapiens | - |
| MDA-MB-231 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-lysine-histone H3 + H2O | deacetylation occurs at Lys9 and Lys23 | Homo sapiens | histone H3 + acetate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HDAC | - |
Homo sapiens |
| HDAC1 | - |
Homo sapiens |
| HDAC2 | - |
Homo sapiens |
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