Activating Compound | Comment | Organism | Structure |
---|---|---|---|
o-aminophenol | activation at 0.2 mM | Rattus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ag+ | complete inhibition at 0.05 mM | Rattus sp. | |
anthranilic acid | 45% inhibition at 0.5 mM | Rattus sp. | |
Cu2+ | 31% inhibition at 1 mM | Rattus sp. | |
Hg2+ | complete inhibition at 0.05 mM | Rattus sp. | |
Na2S2O4 | 27% inhibition at 0.04 mM | Rattus sp. | |
NaAsO2 | 25% inhibition at 0.05 mM | Rattus sp. | |
NaF | 27% inhibition at 10 mM | Rattus sp. | |
NaHSO3 | 24% inhibition at 0.04 mM | Rattus sp. | |
o-aminobenzamidine | 62% inhibition at 0.5 mM | Rattus sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
N-formyl-L-kynurenine | - |
Rattus sp. | |
0.21 | - |
N-formylanthranilic acid | - |
Rattus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-L-kynurenine + H2O | Rattus sp. | - |
L-kynurenine + formate | - |
? | |
N-formyl-o-aminoacetophenone + H2O | Rattus sp. | 60% of activity compared to N-formyl-L-kynurenine | formate + o-aminoacetophenone | - |
? | |
N-formylanthranilic acid + H2O | Rattus sp. | 13.5% activity compared to N-formyl-L-kynurenine | formate + anthranilic acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity, chromatography steps | Rattus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
22.8 | - |
- |
Rattus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formanilide + H2O | poor activity | Rattus sp. | formate + aniline | - |
? | |
N-formyl-L-kynurenine + H2O | - |
Rattus sp. | L-kynurenine + formate | - |
? | |
N-formyl-o-aminoacetophenone + H2O | 60% of activity compared to N-formyl-L-kynurenine | Rattus sp. | formate + o-aminoacetophenone | - |
? | |
N-formylanthranilic acid + H2O | 13.5% activity compared to N-formyl-L-kynurenine | Rattus sp. | formate + anthranilic acid | - |
? |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 9 | optimum range | Rattus sp. |