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Literature summary for 3.5.1.46 extracted from

  • Kinoshita, S.
    Microbial degradation of 6-aminohexanoic acid cyclic dimer and its enzymes (1982), Hakko Kogaku Kaishi, 60, 363-375.
No PubMed abstract available
Search for more literature for 3.5.1.46

Inhibitors

Inhibitors Comment Organism Structure
diisopropyl fluorophosphate inhibition at 0.37 mM Flavobacterium sp.
p-chloromercuribenzoate inhibition at 0.013 mM Flavobacterium sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.9
-
 N-(6-aminohexanoyl)-6-aminohexanoate
-
 Flavobacterium sp.
6.2
-
 N-6-aminohexanoate-trimer
-
 Flavobacterium sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42000
-
 2 * 42000, SDS-PAGE Flavobacterium sp.
84000
-
 gel filtration Flavobacterium sp.

Organism

Organism UniProt Comment Textmining
Flavobacterium sp.
-
-
-
Flavobacterium sp. KI72
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Flavobacterium sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.05
-
-
 Flavobacterium sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-(6-aminohexanoyl)-6-aminohexanoate + H2O
-
 Flavobacterium sp. 6-aminohexanoate + 6-aminohexanoate
-
 ?
N-(6-aminohexanoyl)-6-aminohexanoate + H2O
-
 Flavobacterium sp. KI-72 6-aminohexanoate + 6-aminohexanoate
-
 ?
N-(6-aminohexanoyl)-6-aminohexanoate + H2O
-
 Flavobacterium sp. KI72 6-aminohexanoate + 6-aminohexanoate
-
 ?
N-6-aminohexanoate hexamer + H2O
-
 Flavobacterium sp. 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate hexamer + H2O
-
 Flavobacterium sp. KI-72 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate hexamer + H2O
-
 Flavobacterium sp. KI72 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate icosamer + H2O poor activity, decreasing hydrolysis with increasing polymerization number of oligomers, higher oligomers not hydrolyzed Flavobacterium sp. 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate pentamer + H2O
-
 Flavobacterium sp. 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate pentamer + H2O
-
 Flavobacterium sp. KI-72 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate pentamer + H2O
-
 Flavobacterium sp. KI72 6-aminohexanoate + ?
-
 ?
N-6-aminohexanoate tetramer + H2O
-
 Flavobacterium sp. 6-aminohexanoate + N-6-aminohexanoate trimer
-
 ?
N-6-aminohexanoate tetramer + H2O
-
 Flavobacterium sp. KI-72 6-aminohexanoate + N-6-aminohexanoate trimer
-
 ?
N-6-aminohexanoate tetramer + H2O
-
 Flavobacterium sp. KI72 6-aminohexanoate + N-6-aminohexanoate trimer
-
 ?
N-6-aminohexanoate trimer + H2O
-
 Flavobacterium sp. 6-aminohexanoate + N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
N-6-aminohexanoate trimer + H2O
-
 Flavobacterium sp. KI-72 6-aminohexanoate + N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
N-6-aminohexanoate trimer + H2O
-
 Flavobacterium sp. KI72 6-aminohexanoate + N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 42000, SDS-PAGE Flavobacterium sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
-
 Flavobacterium sp.

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
35
-
 stable for 1 h Flavobacterium sp.

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2
-
 6-aminohexanoate trimer
-
 Flavobacterium sp.
2.4
-
 N-(6-aminohexanoyl)-6-aminohexanoate
-
 Flavobacterium sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9
-
 Flavobacterium sp.

pH Stability

pH Stability pH Stability Maximum Comment Organism
6.5 9.5
-
 Flavobacterium sp.