Application | Comment | Organism |
---|---|---|
medicine | down-regulated state of FAAH - through its effects on CB1 and opioid receptor in the brain reward circuitry - promotes ethanol drinking behavior. Manipulation of the FAAH activity might represent a novel therapeutic target for the treatment of ethanol dependence | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-{[(E)-(cyclohexylimino)(hydroxy)methyl]oxy}biphenyl-3-carboximidic acid | the inhibitor markedly increases the preference for ethanol. The inhibitor specifically acts through FAAH | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | FAAH is a key regulator in the development of ethanol dependence | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | FAAH is a key regulator in the development of ethanol dependence | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAAH | - |
Mus musculus |
fatty acid amide hydrolase | - |
Mus musculus |