Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | intramolecular autoproteolytic activation reaction | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | enzyme deficiency or its absence gives rise to aspartylglycosaminuria, the most common disorder of glycoprotein metabolism | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine + H2O | Homo sapiens | catabolism of N-linked oligosaccharides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | intramolecular autoproteolytic activation reaction | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme catalyzes the hydrolysis of a variety of asparagine and aspartyl compounds containing a free alpha-carboxyl group and a free alpha-amino group, study of enzyme specificity with 14 substrate analogues where the structure of the aspartyl group is changed, the alpha-carboxyl group is necessary for enzyme activity, but not the alpha-amino group, whose position acts as an anchor in the binding site for the substrate, no substrate: N-acetyl-D-glucosamine, intramolecular autoproteolytic activation reaction | Homo sapiens | ? | - |
? | |
N4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine + H2O | catabolism of N-linked oligosaccharides | Homo sapiens | ? | - |
? | |
N4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine + H2O | catalyzes the hydrolysis of the N-glycosylic bond | Homo sapiens | 2-acetamido-2-deoxy-beta-D-glucopyranosylamine + L-asparagine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glycosylasparaginase | - |
Homo sapiens |