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Literature summary for 3.5.1.25 extracted from

  • Yadav, V.; Panilaitis, B.; Shi, H.; Numuta, K.; Lee, K.; Kaplan, D.L.
    N-acetylglucosamine 6-phosphate deacetylase (nagA) is required for N-acetyl glucosamine assimilation in Gluconacetobacter xylinus (2011), PLoS ONE, 6, e18099.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.25

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Top10 cells Komagataeibacter xylinus

Organism

Organism UniProt Comment Textmining
Komagataeibacter xylinus D2KKE6 formally known as Acetobacter xylinum
-
Komagataeibacter xylinus 10245 D2KKE6 formally known as Acetobacter xylinum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Komagataeibacter xylinus D-glucosamine 6-phosphate + acetate
-
 ?
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Komagataeibacter xylinus 10245 D-glucosamine 6-phosphate + acetate
-
 ?

Synonyms

Synonyms Comment Organism
N-acetylglucosamine 6-phosphate deacetylase
-
 Komagataeibacter xylinus
NagA
-
 Komagataeibacter xylinus

General Information

General Information Comment Organism
malfunction UDP-N-acetylglucosamine synthesis and bacterial growth (due to lack of N-acetylglucosamine utilization) is completely inhibited in N-acetylglucosamine 6-phosphate deacetylase disruption mutants Komagataeibacter xylinus
physiological function the enzyme plays an essential role for N-acetylglucosamine assimilation by Gluconacetobacter xylinus thus is required for the growth and survival for the bacterium in presence of N-acetylglucosamine as carbon source Komagataeibacter xylinus