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Literature summary for 3.5.1.23 extracted from

  • Li, J.; Bi, F.C.; Yin, J.; Wu, J.X.; Rong, C.; Wu, J.L.; Yao, N.
    An Arabidopsis neutral ceramidase mutant ncer1 accumulates hydroxyceramides and is sensitive to oxidative stress (2015), Front. Plant Sci., 6, 460 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.23

Cloned(Commentary)

Cloned (Comment) Organism
gene ncer1, transient expression of GFP-tagged enzyme in Arabidosis thaliana protoplasts in the endoplasmic reticulum, quantitative real-time PCR enzyme expression analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information the Arabidopsis thaliana neutral ceramidase DNA insertion mutant ncer1 has no visible phenotype, but accumulates hydroxyceramides, and shows increased sensitivity to oxidative stress induced by methyl viologen. Plants overexpressing AtNCER1 show increased tolerance to oxidative stress. Neutral ceramidase mutants have increased sensitivity to C2-ceramide induced cell death Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum predominantly Arabidopsis thaliana 5783
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana F4HQM3
-
-
Arabidopsis thaliana Col-0 F4HQM3
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-

Synonyms

Synonyms Comment Organism
AtNCER1
-
 Arabidopsis thaliana
ncer1
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 Arabidopsis thaliana
neutral ceramidase
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 Arabidopsis thaliana

General Information

General Information Comment Organism
evolution the Arabidopsis thaliana ceramidase AtNCER1 is a homologue of human neutral ceramidase Arabidopsis thaliana