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Literature summary for 3.5.1.23 extracted from

  • Lucki, N.; Sewer, M.B.
    The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells (2009), Biochim. Biophys. Acta, 1791, 706-713.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
cAMP-responsive element binding protein CREB is a central regulator os ASAH1 gene transcription Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
the human ASAH1 promoter is cloned Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens ceramidase catalyzes the hydrolysis of ceramide into sphingosine and a free fatty acid ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
NCI-H295R cell human adrenocortical cell Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ceramidase catalyzes the hydrolysis of ceramide into sphingosine and a free fatty acid Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
acid ceramidase
-
Homo sapiens
ASAH1
-
Homo sapiens
ceramidase
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
activity assay Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
activity assay Homo sapiens