Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
F508del mouse, mouse model with well-characterized intestinal pathology | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gut | - |
Mus musculus | - |
intestine | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
mucosa | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000000053 | - |
homozygous F508del mice, lung | Mus musculus |
0.000000055 | - |
wild-type mice, lung | Mus musculus |
0.000000056 | - |
heterozygous F508del mice, lung | Mus musculus |
0.000002 | - |
heterozygous F508del mice, spleen | Mus musculus |
0.000002 | - |
wild-type mice, spleen | Mus musculus |
0.0000028 | - |
homozygous F508del mice, spleen | Mus musculus |
0.0000035 | - |
wild-type mice, lung | Mus musculus |
0.00000375 | - |
heterozygous F508del mice, lung | Mus musculus |
0.00000416 | - |
homozygous F508del mice, lung | Mus musculus |
0.00001 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000127 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000137 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000145 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000155 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000163 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000167 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000187 | - |
wild-type mice, kidney | Mus musculus |
0.0000188 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000192 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000193 | - |
homozygous F508del mice, kidney | Mus musculus |
0.00002 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000208 | - |
heterozygous F508del mice, kidney | Mus musculus |
0.0000208 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000215 | - |
wild-type mice, liver | Mus musculus |
0.0000227 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.000023 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000238 | - |
homozygous F508del mice, liver | Mus musculus |
0.0000255 | - |
heterozygous F508del mice, liver | Mus musculus |
0.0000272 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000273 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000292 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000308 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000417 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.000048 | - |
wild-type mice, mucosal homogenates | Mus musculus |
0.0000542 | - |
homozygous F508del mice, mucosal homogenates | Mus musculus |
0.0000625 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
0.0001 | - |
heterozygous F508del mice, mucosal homogenates | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
octanoyl-D-erythro-sphingosine + H2O | substrate activity assay | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid ceramidase | - |
Mus musculus |
CDase | - |
Mus musculus |
neutral ceramidase | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
activity assay | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
activity assay | Mus musculus |
7 | - |
activity assay | Mus musculus |