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BRENDA support

Literature summary for 3.5.1.2 extracted from

  • Holten, A.T.; Gundersen, V.
    Glutamine as a precursor for transmitter glutamate, aspartate and GABA in the cerebellum: a role for phosphate-activated glutaminase (2008), J. Neurochem., 104, 1032-1042.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
6-diazo-5-oxo-L-norleucine
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Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
nerve terminal parallel-fiber terminals contain a glutaminase activity that could sustain the glutamate levels during synaptic activity given that the terminals are provided with glutamine. The nerve terminal aspartate and GABA could be produced from glutamine in a reaction dependent on glutaminase activity Rattus norvegicus
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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adult Wistar
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