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Literature summary for 3.5.1.2 extracted from

  • Ardawi, M.S.M.; Newsholme, E.A.
    Intracellular localization and properties of phosphate-dependent glutaminase in rat mesenteric lymph nodes (1984), Biochem. J., 217, 289-296.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.2

Activating Compound

Activating Compound Comment Organism Structure
ATP activates enzyme from mesenteric lymph nodes Rattus norvegicus
CTP activates enzyme from mesenteric lymph nodes Rattus norvegicus
D-fructose 6-phosphate activates enzyme from mesenteric lymph nodes Rattus norvegicus
D-glucose 6-phosphate activates enzyme from mesenteric lymph nodes Rattus norvegicus
GTP activates enzyme from mesenteric lymph nodes Rattus norvegicus
ITP activates enzyme from mesenteric lymph nodes Rattus norvegicus
Leu activates enzyme from mesenteric lymph nodes, 50% activation at 0.6 mM Rattus norvegicus
NH4+ enzyme from mesenteric lymph nodes, 50% activation at 5 mM Rattus norvegicus
phosphate dependent on Rattus norvegicus
phosphoenolpyruvate activates enzyme from mesenteric lymph nodes, 50% activation at 0.2 mM Rattus norvegicus
sulfate activates enzyme from mesenteric lymph nodes Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
2-oxoglutarate enzyme from mesenteric lymph nodes Rattus norvegicus
citrate enzyme from mesenteric lymph nodes Rattus norvegicus
diazo-5-oxo-L-norleucine enzyme from mesenteric lymph nodes Rattus norvegicus
glutamate
-
 Rattus norvegicus
Mersalyl enzyme from mesenteric lymph nodes Rattus norvegicus
NEM enzyme from mesenteric lymph nodes Rattus norvegicus
NH4+ enzyme from mesenteric lymph nodes Rattus norvegicus
succinate enzyme from mesenteric lymph nodes Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2
-
 Gln
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
mesenteric lymph node
-
 Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-
thymus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gln + H2O
-
 Rattus norvegicus Glu + NH3
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.6
-
-
 Rattus norvegicus