General Stability | Organism |
---|---|
pure enzyme extremely unstable | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aspartic acid | 0.002 M, 20-25% inhibition | Rattus norvegicus | |
glutamic acid | 0.002 M, 20-25% inhibition | Rattus norvegicus | |
N-ethylmaleimide | - |
Rattus norvegicus | |
p-hydroxymercuribenzoate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
N-acyl L-aspartic acid | - |
Sus scrofa | |
0.2 | - |
N-acyl L-aspartic acid | brain enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-L-aspartic acid + H2O | Rattus norvegicus | - |
acetate + aspartic acid | - |
? | |
N-acetyl-L-aspartic acid + H2O | Sus scrofa | - |
acetate + aspartic acid | - |
? | |
N-acetyl-L-aspartic acid + H2O | Gallus sp. | - |
acetate + aspartic acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus sp. | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Sus scrofa | - |
pig | - |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
brain | - |
Sus scrofa | - |
brain | - |
Gallus sp. | - |
kidney | - |
Rattus norvegicus | - |
kidney | - |
Sus scrofa | - |
kidney | - |
Gallus sp. | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Gallus sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.47 | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, frozen storage of undialyzed enzyme for a few days leads to a complete disappearance of activity following a single thaw | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | N-methyl aspartic acid, N-carbamoyl aspartic acid and N-glycyl aspartic acids are no substrates | Rattus norvegicus | ? | - |
? | |
N-acetyl-L-aspartic acid + H2O | - |
Rattus norvegicus | acetate + aspartic acid | - |
? | |
N-acetyl-L-aspartic acid + H2O | - |
Sus scrofa | acetate + aspartic acid | - |
? | |
N-acetyl-L-aspartic acid + H2O | - |
Gallus sp. | acetate + aspartic acid | - |
? | |
N-acyl L-aspartic acid + H2O | - |
Rattus norvegicus | acetate + L-aspartate | - |
? | |
N-acyl L-aspartic acid + H2O | - |
Sus scrofa | acetate + L-aspartate | - |
? | |
N-acyl L-aspartic acid + H2O | - |
Gallus sp. | acetate + L-aspartate | - |
? | |
N-formyl aspartic acid + H2O | - |
Rattus norvegicus | formate + aspartate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-acetyl-aspartate deacetylase | - |
Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
57 | - |
rapidly denatures above | Rattus norvegicus |
70 | - |
stable at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8.5 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
3 | 10 | - |
Rattus norvegicus |