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Literature summary for 3.5.1.13 extracted from

  • Manoharan, I.; Boopathy, R.
    Diisopropylfluorophosphate-sensitive aryl acylamidase activity of fatty acid free human serum albumin (2006), Arch. Biochem. Biophys., 452, 186-188.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
diisopropylfluorophosphate complete inhibition of aryl acylacylamidase activity of fatty acid free human albumin at 2 mM, covalent binding to the catalytic site Tyr411 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular serum Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the reaction in human erythrocytes and plasma is performed by the butyrylcholinesterase, EC 3.1.1.8, which is inactive with butyrylthiocholine, also fatty acid free human albumin has aryl acylacylamidase activity, which accounts for 10% of total human enzyme activity ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-
erythrocyte
-
Homo sapiens
-
serum
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-nitroacetanilide + H2O the reaction in human erythrocytes and plasma is performed by the butyrylcholinesterase, EC 3.1.1.8, which is inactive with butyrylthiocholine, also fatty acid free human albumin has aryl acylacylamidase activity, which accounts for 10% of total human enzyme activity Homo sapiens 2-nitroaniline + acetate
-
?
additional information the reaction in human erythrocytes and plasma is performed by the butyrylcholinesterase, EC 3.1.1.8, which is inactive with butyrylthiocholine, also fatty acid free human albumin has aryl acylacylamidase activity, which accounts for 10% of total human enzyme activity Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
aryl acylamidase
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40 50 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Homo sapiens