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Literature summary for 3.5.1.108 extracted from
- Insights into the zinc-dependent deacetylase LpxC biochemical properties and inhibitor design (2016), Curr. Top. Med. Chem., 16, 2379-2430 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | promising target in the development of novel antibiotics against Gram-negative bacteria | Aquifex aeolicus |
| medicine | promising target in the development of novel antibiotics against Gram-negative bacteria | Pseudomonas aeruginosa |
| medicine | promising target in the development of novel antibiotics against Gram-negative bacteria | Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (2R)-4-(2'-ethyl[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa |  |
| (2R)-4-(2'-fluoro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(3'-chloro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(4'-cyano[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(4'-fluoro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(4-cyclohexyl-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(4-tert-butyl-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-(5-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[3-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[3-(2-fluoro-3-methoxyphenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[3-(2-fluoro-4-methoxyphenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4'-(3-aminopropoxy)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4'-(3-carbamimidamidopropoxy)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4'-(aminomethyl)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2,3-dichlorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2,3-difluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2,5-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2,6-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2-chloro-4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2-fluoro-3-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(2H-1,3-benzodioxol-5-yl)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3,4-dichlorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3,4-difluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3,5-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3,5-dimethylphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(3-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(4-chloro-2,3-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(4-chloro-2-fluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(4-chloro-2-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(4-chloro-3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(4-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(benzyloxy)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(cyclohex-1-en-1-yl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[4-(cyclopentyloxy)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[5-(2,3-dichlorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[5-(2-fluoro-4-methoxyphenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[5-(2-fluorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-4-[5-(3-fluorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(1-phenyl-1H-1,2,3-triazol-4-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(1-phenyl-1H-pyrazol-4-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2'-oxo[2,4'-bipyridin]-1'(2'H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo-4-phenylpyrimidin-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo[4,4'-bipyridin]-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(3-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(3-phenyl-1,2-oxazol-5-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(4-phenyl-1H-1,2,3-triazol-1-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(4-phenyl-1H-pyrazol-1-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-phenyl-1,2-oxazol-3-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-phenylpyridin-2-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-oxo-4-phenylpyrimidin-1(6H)-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-phenylpyridin-3-yl)butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(2,3,4-trifluorophenyl)pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(phenylethynyl)pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[(E)-2-phenylethenyl]pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(1,3-thiazol-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(pyridin-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(pyridin-4-yl)phenyl]pyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3'-(1H-pyrazol-1-yl)[1,1'-biphenyl]-4-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3'-(propan-2-yl)[1,1'-biphenyl]-4-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3-(4-methylphenyl)-1,2-oxazol-5-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(4-methylphenyl)-1H-1,2,3-triazol-1-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(naphthalen-2-yl)-2-oxopyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(phenylsulfanyl)phenyl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(pyridin-3-yl)phenyl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-[(pyridin-4-yl)oxy]phenyl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-[4-(1,2-oxazol-3-yl)phenyl]-2-oxopyridin-1(2H)-yl]butanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-(2'-methoxy[1,1'-biphenyl]-4-yl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-(6-methoxy-2'-oxo[3,4'-bipyridin]-1'(2'H)-yl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(2-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(3-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-[4-(2-methoxypyrimidin-5-yl)phenyl]-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-[4-(5-methoxypyrimidin-2-yl)phenyl]-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-4-(2-hydroxy-6-phenylpyridin-3-yl)-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2R)-N-hydroxy-4-[4'-(hydroxyacetyl)[1,1'-biphenyl]-4-yl]-2-(methanesulfonyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]propanamide | - |
Escherichia coli | |
| (2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]propanamide | - |
Escherichia coli | |
| (2S)-N1-hydroxy-2-[4-(phenylethynyl)benzamido]butanediamide | - |
Pseudomonas aeruginosa | |
| (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,2-oxazol-5-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,3-oxazol-2-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2S,3R)-2-[5-([1,1'-biphenyl]-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | - |
Escherichia coli | |
| (2S,3R)-2-[5-[([1,1'-biphenyl]-3-yl)ethynyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | - |
Escherichia coli | |
| (2S,3R)-2-[5-[([1,1'-biphenyl]-4-yl)ethynyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | - |
Escherichia coli | |
| (2S,3R)-N,3-dihydroxy-2-(1-oxo-5-phenyl-1,3-dihydro-2H-isoindol-2-yl)butanamide | - |
Escherichia coli | |
| (2S,3R)-N,3-dihydroxy-2-[1-oxo-5-(phenylethynyl)-1,3-dihydro-2H-isoindol-2-yl]butanamide | - |
Escherichia coli | |
| (2S,3R)-N,3-dihydroxy-2-[1-oxo-5-[4-(phenylethynyl)phenyl]-1,3-dihydro-2H-isoindol-2-yl]butanamide | - |
Escherichia coli | |
| (2S,3R)-N,3-dihydroxy-2-[1-oxo-6-(phenylethynyl)-1,3-dihydro-2H-isoindol-2-yl]butanamide | - |
Escherichia coli | |
| (2S,3R)-N,3-dihydroxy-2-[3-oxo-6-(phenylethynyl)-1,3-dihydro-2H-indazol-2-yl]butanamide | - |
Escherichia coli | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-5-ethoxy-N,3-dihydroxy-2-methylpentanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2,4-dimethylpentanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,2-oxazol-3-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1-methyl-1H-1,2,3-triazol-5-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1-methyl-1H-imidazol-2-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1H-pyrazol-5-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(5-methyl-1,2-oxazol-3-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(pyridin-2-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(pyridin-3-yl)propanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-phenylpropanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylheptanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylpentanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-3-(1H-imidazol-5-yl)-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-3-[5-(hydroxymethyl)-1,2-oxazol-3-yl]-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(1-benzothiophen-2-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 10% inhibition | Escherichia coli | |
| (4R)-2-(1-butyl-1H-indazol-3-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(2,4-dichlorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 32% inhibition | Escherichia coli | |
| (4R)-2-(2-butyl-2H-indazol-3-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(2H-1,3-benzodioxol-5-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 46% inhibition | Escherichia coli | |
| (4R)-2-(3,4-dichlorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 68% inhibition | Escherichia coli | |
| (4R)-2-(3,4-difluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 60% inhibition | Escherichia coli | |
| (4R)-2-(3,4-dimethoxy-5-propylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 96% inhibition | Escherichia coli | |
| (4R)-2-(3,5-dichlorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 61% inhibition | Escherichia coli | |
| (4R)-2-(3,5-difluoro-4-methoxyphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 85% inhibition | Escherichia coli | |
| (4R)-2-(3,5-difluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 37% inhibition | Escherichia coli | |
| (4R)-2-(3,5-dimethoxy-4-methylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 37% inhibition | Escherichia coli | |
| (4R)-2-(3,5-dimethoxyphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 67% inhibition | Escherichia coli | |
| (4R)-2-(3-bromo-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 66% inhibition | Escherichia coli | |
| (4R)-2-(3-bromo-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(3-bromo-5-fluoro-4-methoxyphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(3-chloro-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 69% inhibition | Escherichia coli | |
| (4R)-2-(3-chloro-5-fluoro-1H-indol-2-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(3-cyanophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 54% inhibition | Escherichia coli | |
| (4R)-2-(3-ethoxy-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(3-fluoro-4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(3-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-acetylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-bromophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-butylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 56% inhibition | Escherichia coli | |
| (4R)-2-(4-butylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-chloro-3-nitrophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 70% inhibition | Escherichia coli | |
| (4R)-2-(4-ethoxy-3-oxobutyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 18% inhibition | Escherichia coli | |
| (4R)-2-(4-fluoro-3-methylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 59% inhibition | Escherichia coli | |
| (4R)-2-(4-fluoro-3-methylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-fluoro-3-nitrophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 57% inhibition | Escherichia coli | |
| (4R)-2-(4-fluoro-3-propylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(4-tert-butylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 58% inhibition | Escherichia coli | |
| (4R)-2-(5-fluoro-1H-indol-2-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-(adamantan-1-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 71% inhibition | Escherichia coli | |
| (4R)-2-([1,1'-biphenyl]-4-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 69% inhibition | Escherichia coli | |
| (4R)-2-benzyl-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 34% inhibition | Escherichia coli | |
| (4R)-2-cyclopentyl-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 7% inhibition | Escherichia coli | |
| (4R)-2-dodecyl-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 60% inhibition | Escherichia coli | |
| (4R)-2-[(4-chlorophenyl)methyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 12% inhibition | Escherichia coli | |
| (4R)-2-[(E)-2-(2-chlorophenyl)ethenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 36% inhibition | Escherichia coli | |
| (4R)-2-[(E)-2-(4-fluorophenyl)ethenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 50% inhibition | Escherichia coli | |
| (4R)-2-[2-(ethylsulfanyl)pyridin-3-yl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 18% inhibition | Escherichia coli | |
| (4R)-2-[3,5-bis(trifluoromethyl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 57% inhibition | Escherichia coli | |
| (4R)-2-[3-(benzyloxy)-4-methoxyphenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 8% inhibition | Escherichia coli | |
| (4R)-2-[3-chloro-4-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[3-fluoro-4-(trifluoromethyl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 55% inhibition | Escherichia coli | |
| (4R)-2-[3-fluoro-4-[(prop-2-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[3-fluoro-5-(trifluoromethyl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 12% inhibition | Escherichia coli | |
| (4R)-2-[4-(benzyloxy)-3,5-dimethylphenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 61% inhibition | Escherichia coli | |
| (4R)-2-[4-(benzyloxy)-3-methoxyphenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 13% inhibition | Escherichia coli | |
| (4R)-2-[4-(dimethylamino)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[4-(hexyloxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 86% inhibition | Escherichia coli | |
| (4R)-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 77% inhibition | Escherichia coli | |
| (4R)-2-[4-[(3-fluorophenyl)methoxy]-3-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[4-[(but-3-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[4-[(but-3-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[4-[(but-3-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-thiazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-2-[5-fluoro-4-methoxy-2-methyl-3-(prop-2-en-1-yl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(1H-indazol-3-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(2,3,4-trifluorophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 25% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(2,3,5-trifluoro-4-methoxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 35% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(2-phenylcyclopropyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 31% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(2-phenylethyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 32% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(3,4,5-triethoxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 86% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(3,4,5-trifluorophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 54% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 72% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(3-methoxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 44% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4'-propyl[1,1'-biphenyl]-4-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(4-iodophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(4-methoxy-3,5-dimethylphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 71% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4-methoxy-3-nitrophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 78% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4-methoxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 61% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4-methyl-3-nitrophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 79% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4-methylphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 57% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-(9-oxo-9H-fluoren-1-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 1% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(naphthalen-1-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 19% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(naphthalen-2-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 35% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-(thiophen-2-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 19% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(1S,4R)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptan-1-yl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 8% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(4-methoxyphenyl)methyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 10% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(E)-2-(4-methoxyphenyl)ethenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 48% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(E)-2-(4-nitrophenyl)ethenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 1% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(E)-2-phenylethenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 39% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(E)-2-[3-(trifluoromethyl)phenyl]ethenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 32% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[(thiophen-2-yl)methyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 17% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 64% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 59% inhibition; 0.001 mg/ml, 65% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 79% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-methoxy-3,5-bis(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-thiazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-methoxy-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-methoxy-3-propyl-5-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-[(3-methylbut-2-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-[(3-nitrophenoxy)methyl]phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-[(3-nitrophenyl)methoxy]phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-[(E)-phenyldiazenyl]phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | 0.001 mg/ml, 71% inhibition | Escherichia coli | |
| (4R)-N-hydroxy-2-[4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| (4R)-N-hydroxy-2-[6-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-1,3-oxazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 1,5-anhydro-2,3-dideoxy-2-[2-(hydroxyamino)-2-oxoethyl]-D-ribo-hexitol | - |
Escherichia coli | |
| 1,5-anhydro-2,4-dideoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-xylo-hexitol | 0.001 mg/ml, 18% inhibition | Escherichia coli | |
| 1,5-anhydro-2,6-dideoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-glucitol | 0.001 mg/ml, 15% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-glucitol | 0.001 mg/ml, 51% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecyl-D-glucitol | 0.001 mg/ml, 13% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-[(3S)-3-hydroxyhexadecanoyl]-D-glucitol | - |
Escherichia coli | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-[(3S)-3-hydroxyhexadecanoyl]-D-glucitol | - |
Pseudomonas aeruginosa | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-4-O-methyl-3-O-tetradecanoyl-D-glucitol | 0.001 mg/ml, 30% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-6-O-methyl-3-O-tetradecanoyl-D-glucitol | 0.001 mg/ml, 3% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-3-O-hexadecanoyl-2-[2-(hydroxyamino)-2-oxoethyl]-D-glucitol | 0.001 mg/ml, 11% inhibition | Escherichia coli | |
| 1,5-anhydro-2-deoxy-3-O-hexanoyl-2-[2-(hydroxyamino)-2-oxoethyl]-D-glucitol | - |
Escherichia coli | |
| 1,5-anhydro-2-deoxy-3-O-hexanoyl-2-[[hydroxy(methyl)phosphoryl]methyl]-D-glucitol | - |
Escherichia coli | |
| 1,5-anhydro-2-deoxy-3-O-hexanoyl-2-[[hydroxy(methyl)phosphoryl]methyl]-D-glucitol | - |
Pseudomonas aeruginosa | |
| 1,5-anhydro-3-O-benzoyl-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-D-glucitol | 0.001 mg/ml, 53% inhibition | Escherichia coli | |
| 1-benzyl-N-hydroxy-4-[4-(phenylethynyl)benzamido]piperidine-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 1-hydroxy-4-[4-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl]phenoxy]pyridin-1-ium | - |
Pseudomonas aeruginosa | |
| 2-(4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-thiazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 2-(5-fluoro-1H-indol-2-yl)-N-hydroxy-5,6-dihydro-4H-1,3-oxazine-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| 2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-hydroxy-5,6-dihydro-4H-1,3-oxazine-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 2-[[([1,1'-biphenyl]-4-yl)oxy]methyl]-N,3-dihydroxy-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| 3-([1,1'-biphenyl]-4-sulfonyl)-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| 3-ethoxy-4-fluoro-N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]benzamide | - |
Pseudomonas aeruginosa | |
| 3-[([1,1'-biphenyl]-4-yl)oxy]-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| 3-[([1,1'-biphenyl]-4-yl)sulfanyl]-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | - |
Pseudomonas aeruginosa | |
| 4'-ethyl-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl][1,1'-biphenyl]-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-3-carboxamide | - |
Pseudomonas aeruginosa | |
| 4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-4-carboxylic acid | - |
Pseudomonas aeruginosa | |
| 4-(4-[[4-(cyanomethyl)phenyl]ethynyl]phenyl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(hydroxymethyl)-2-methylbutanamide | - |
Pseudomonas aeruginosa | |
| 4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)butanamide | - |
Pseudomonas aeruginosa | |
| 4-([1,1'-biphenyl]-4-yl)-N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-([1,1'-biphenyl]-4-yl)-N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]piperidine-1-carboxamide | - |
Escherichia coli | |
| 4-([1,1'-biphenyl]-4-yl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-([1,1'-biphenyl]-4-yl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperidine-1-carboxamide | - |
Escherichia coli | |
| 4-([4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-4-yl]oxy)butanoic acid | - |
Pseudomonas aeruginosa | |
| 4-([4-[(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl)ethynyl]phenoxy]methyl)-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4-([[4-(4-chlorophenoxy)phenyl]sulfanyl]methyl)-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4-[(4-[[4-([2-[(dimethylamino)methyl]morpholin-4-yl]methyl)phenyl]ethynyl]phenoxy)methyl]-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4-[(but-3-en-1-yl)oxy]-N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]benzamide | - |
Pseudomonas aeruginosa | |
| 4-[4-[(4-aminophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-[4-[(4-chlorophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-[4-[(4-fluorophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| 4-[[([1,1'-biphenyl]-4-yl)oxy]methyl]-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4-[[4-(benzyloxy)phenoxy]methyl]-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 4-[[4-([4-[(4-acetylpiperazin-1-yl)methyl]phenyl]ethynyl)phenoxy]methyl]-N-hydroxyoxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| 5'-deoxy-5'-[2-([(E)-[(2,3,4-trihydroxyphenyl)methylidene]amino]oxy)acetamido]uridine | - |
Escherichia coli | |
| 5'-O-[(E)-[(2,3,4-trihydroxyphenyl)methylidene]amino]uridine | - |
Escherichia coli | |
| 5'-O-[(E)-[(3,4-dihydroxyphenyl)methylidene]amino]uridine | - |
Escherichia coli | |
| 5-ethyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperidin-1-yl]ethyl)imidazolidine-2,4-dione | - |
Escherichia coli | |
| 5-methyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperazin-1-yl]ethyl)imidazolidine-2,4-dione | - |
Escherichia coli | |
| 5-methyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperidin-1-yl]ethyl)imidazolidine-2,4-dione | - |
Escherichia coli | |
| N-hydroxy-1,1-dioxo-4-[4-(phenylethynyl)benzamido]-1lambda6-thiane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-2-[(1R)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | - |
Escherichia coli | |
| N-hydroxy-2-[(1R)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | - |
Escherichia coli | |
| N-hydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | - |
Escherichia coli | |
| N-hydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | - |
Escherichia coli | |
| N-hydroxy-2-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-thiazole-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-2-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]methoxy]acetamide | - |
Escherichia coli | |
| N-hydroxy-4-([4-[(4-[[4-(propan-2-yl)piperazin-1-yl]methyl]phenyl)ethynyl]phenoxy]methyl)oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-([[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]sulfanyl]methyl)oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-methoxy-1-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenoxy]methyl]cyclohexane-1-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[(4-phenoxyphenoxy)methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[(4-[[4-([4-[2-(1H-imidazol-1-yl)ethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[(4-[[4-([4-[2-(morpholin-4-yl)-2-oxoethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[(4-[[4-([4-[2-(morpholin-4-yl)ethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[(4-[[4-([[(4-methoxyphenyl)methyl]amino]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[4-(phenylethynyl)benzamido]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[4-(phenylethynyl)benzamido]piperidine-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[4-(phenylethynyl)benzamido]thiane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[[4-(4-phenylbuta-1,3-diyn-1-yl)phenoxy]methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[[4-(5-hydroxy-5-methylhexa-1,3-diyn-1-yl)phenoxy]methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[[4-([4-[(4-methylpiperazin-1-yl)methyl]phenyl]ethynyl)phenoxy]methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzene-1-sulfinyl]methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-4-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenoxy]methyl]oxane-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N-hydroxy-N2-([2-[4-(phenylethynyl)phenyl]ethyl]carbamoyl)-L-threoninamide | - |
Escherichia coli | |
| N-hydroxy-N2-([[4-(phenylethynyl)phenyl]methyl]carbamoyl)-L-threoninamide | - |
Escherichia coli | |
| N-hydroxy-Nalpha-[4-(phenylethynyl)benzoyl]-L-histidinamide | - |
Pseudomonas aeruginosa | |
| N-[(1R)-2-(hydroxyamino)-2-oxo-1-phenylethyl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(1S)-2-(hydroxyamino)-2-oxo-1-phenylethyl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-1-(hydroxyamino)-3-(methanesulfonyl)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-1-(hydroxyamino)-3-(methylsulfanyl)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-1H-indazole-3-carboxamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(trifluoromethoxy)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethoxy)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2S)-3-amino-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2S)-3-amino-1-(hydroxyamino)-1-oxopropan-2-yl]-4-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-amino-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[3-(phenylethynyl)phenyl]pyrrolidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[4-(phenylethynyl)phenyl]pyrrolidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(hydroxymethyl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(morpholin-4-yl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(piperazin-1-yl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(trifluoromethyl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)piperidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-phenylpiperidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4'-(morpholin-4-yl)[1,1'-biphenyl]-4-yl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(1,3-thiazol-5-yl)phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(4-hydroxyphenyl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyrazin-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-3-yl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-4-yl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(thiophen-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | - |
Escherichia coli | |
| N-[1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[1-(hydroxyamino)-2-methyl-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[1-(hydroxycarbamoyl)cyclobutyl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[1-(hydroxycarbamoyl)cyclohexyl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[2-(hydroxyamino)-2-oxoethyl]-4-(phenylethynyl)benzamide | - |
Pseudomonas aeruginosa | |
| N-[3-hydroxy-1-(hydroxyamino)-2-methyl-1-oxopropan-2-yl][1,1'-biphenyl]-4-carboxamide | - |
Pseudomonas aeruginosa | |
| N1-hydroxy-N2-[4-(phenylethynyl)benzoyl]-N4-prop-2-yn-1-yl-L-aspartamide | - |
Pseudomonas aeruginosa | |
| N1-hydroxy-N4-(2-methoxyethyl)-N2-[4-(phenylethynyl)benzoyl]-L-aspartamide | - |
Pseudomonas aeruginosa | |
| N1-hydroxy-N4-(3-hydroxypropyl)-N2-[4-(phenylethynyl)benzoyl]-L-aspartamide | - |
Pseudomonas aeruginosa | |
| [2-[(4R)-4-(hydroxycarbamoyl)-4,5-dihydro-1,3-oxazol-2-yl]phenyl]methyl benzoate | 0.001 mg/ml, 35% inhibition | Escherichia coli | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | Zn2+-dependent metalloamidase | Aquifex aeolicus | |
| Zn2+ | Zn2+-dependent metalloamidase | Pseudomonas aeruginosa | |
| Zn2+ | Zn2+-dependent metalloamidase | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aquifex aeolicus | O67648 | - |
- |
| Escherichia coli | P0A727 | - |
- |
| Pseudomonas aeruginosa | P47205 | - |
- |
| Pseudomonas aeruginosa ATCC 15692 | P47205 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Aquifex aeolicus | UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Pseudomonas aeruginosa | UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Escherichia coli | UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Pseudomonas aeruginosa ATCC 15692 | UDP-3-O-[(1-hexanoylamino)-1-oxopropan-2-yl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Aquifex aeolicus | UDP-3-O-[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Pseudomonas aeruginosa | UDP-3-O-[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Escherichia coli | UDP-3-O-[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine + H2O | - |
Pseudomonas aeruginosa ATCC 15692 | UDP-3-O-[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + acetate | - |
? | |
| UDP-N-acetyl-alpha-D-glucosamine + H2O | - |
Escherichia coli | UDP-alpha-D-glucosamine + acetate | - |
? | |
| UDP-N-acetylglucosamine + H2O | - |
Aquifex aeolicus | UDP-D-glucosamine + acetate | - |
? | |
| UDP-N-acetylglucosamine + H2O | - |
Pseudomonas aeruginosa | UDP-D-glucosamine + acetate | - |
? | |
| UDP-N-acetylglucosamine + H2O | - |
Pseudomonas aeruginosa ATCC 15692 | UDP-D-glucosamine + acetate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LpxC | - |
Aquifex aeolicus |
| LpxC | - |
Pseudomonas aeruginosa |
| LpxC | - |
Escherichia coli |
| UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase | - |
Aquifex aeolicus |
| UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase | - |
Pseudomonas aeruginosa |
| UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase | - |
Escherichia coli |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000008 | - |
N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.000066 | - |
N-hydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.000095 | - |
N-hydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.000358 | - |
(2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]propanamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.00145 | - |
N-hydroxy-2-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]methoxy]acetamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.0044 | - |
N-hydroxy-2-[(1R)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.0273 | - |
N-hydroxy-2-[(1R)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.0276 | - |
(2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]propanamide | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.19 | - |
1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-[(3S)-3-hydroxyhexadecanoyl]-D-glucitol | pH not specified in the publication, 30°C | Escherichia coli | |
| 0.65 | - |
1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-glucitol | pH not specified in the publication, 30°C | Escherichia coli | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0000002 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-([[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]sulfanyl]methyl)oxane-4-carboxamide | |
| 0.0000003 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | |
| 0.0000004 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,2-oxazol-3-yl)propanamide | |
| 0.0000004 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1H-pyrazol-5-yl)propanamide | |
| 0.0000004 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(5-methyl-1,2-oxazol-3-yl)propanamide | |
| 0.000000511 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-phenyl-1,2-oxazol-3-yl)butanamide | |
| 0.00000052 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(4-chloro-2,3-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000053 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | |
| 0.0000006 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-3-[5-(hydroxymethyl)-1,2-oxazol-3-yl]-2-methylpropanamide | |
| 0.00000064 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(4'-cyano[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000000657 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(4-chloro-2-fluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000008 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,2-oxazol-5-yl)propanamide | |
| 0.0000008 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-3-(1H-imidazol-5-yl)-2-methylpropanamide | |
| 0.00000085 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(4-phenyl-1H-1,2,3-triazol-1-yl)butanamide | |
| 0.000000912 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(4-chloro-3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(4-chloro-2-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(1,3-thiazol-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | |
| 0.0000011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-[4-(1,2-oxazol-3-yl)phenyl]-2-oxopyridin-1(2H)-yl]butanamide | |
| 0.0000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2H-1,3-benzodioxol-5-yl)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(pyridin-4-yl)phenyl]pyridin-1(2H)-yl]butanamide | |
| 0.0000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(naphthalen-2-yl)-2-oxopyridin-1(2H)-yl]butanamide | |
| 0.0000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-[4-(5-methoxypyrimidin-2-yl)phenyl]-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | |
| 0.0000013 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[4-(pyridin-2-yl)phenyl]pyridin-1(2H)-yl]butanamide | |
| 0.00000136 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(2'-fluoro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000137 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000139 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(4-methylphenyl)-1H-1,2,3-triazol-1-yl]butanamide | |
| 0.0000015 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(2,3,4-trifluorophenyl)pyridin-1(2H)-yl]butanamide | |
| 0.00000161 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(4-phenyl-1H-pyrazol-1-yl)butanamide | |
| 0.00000167 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3,4-dichlorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000017 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[(4-[[4-([4-[2-(morpholin-4-yl)-2-oxoethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | |
| 0.00000174 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(4'-fluoro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000018 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2-fluoro-3-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000018 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(phenylethynyl)pyridin-1(2H)-yl]butanamide | |
| 0.00000185 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-4-[4'-(hydroxyacetyl)[1,1'-biphenyl]-4-yl]-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000187 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3,4-difluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000195 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2,3-dichlorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000002 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000002 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-[4-(2-methoxypyrimidin-5-yl)phenyl]-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | |
| 0.000002 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[(4-[[4-([4-[2-(1H-imidazol-1-yl)ethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | |
| 0.000002 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.0000021 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | |
| 0.0000022 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000023 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(5-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000232 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[5-(2-fluoro-4-methoxyphenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000024 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | |
| 0.0000025 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-([1,1'-biphenyl]-4-yl)-N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]piperidine-1-carboxamide | |
| 0.0000026 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | |
| 0.0000026 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-([4-[(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl)ethynyl]phenoxy]methyl)-N-hydroxyoxane-4-carboxamide | |
| 0.00000266 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[5-(2,3-dichlorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000027 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[(4-[[4-([4-[2-(morpholin-4-yl)ethyl]piperazin-1-yl]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | |
| 0.0000029 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(4-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000293 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3-(4-methylphenyl)-1,2-oxazol-5-yl]butanamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3-fluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(1-phenyl-1H-1,2,3-triazol-4-yl)butanamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1,3-oxazol-2-yl)propanamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylbutanamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-[[4-([4-[(4-acetylpiperazin-1-yl)methyl]phenyl]ethynyl)phenoxy]methyl]-N-hydroxyoxane-4-carboxamide | |
| 0.000003 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(morpholin-4-yl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | |
| 0.00000302 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(3-phenyl-1,2-oxazol-5-yl)butanamide | |
| 0.0000031 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzene-1-sulfinyl]methyl]oxane-4-carboxamide | |
| 0.0000032 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-[(E)-2-phenylethenyl]pyridin-1(2H)-yl]butanamide | |
| 0.0000033 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(hydroxymethyl)-2-methylbutanamide | |
| 0.00000354 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(3'-chloro[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000036 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | |
| 0.0000037 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(3-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | |
| 0.0000039 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3,5-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000004 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3R)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylbutanamide | |
| 0.000004 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(4-hydroxyphenyl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.000004 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-4-yl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.0000041 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(cyclohex-1-en-1-yl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000044 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[3-(2-fluoro-4-methoxyphenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000044 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2,5-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000044 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S)-N1-hydroxy-2-[4-(phenylethynyl)benzamido]butanediamide | |
| 0.0000044 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenoxy]methyl]oxane-4-carboxamide | |
| 0.00000471 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2-chloro-4-methoxyphenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000048 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2,6-difluorophenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000049 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000005 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-[4-[(4-chlorophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.00000516 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(benzyloxy)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000053 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(3,5-dimethylphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000053 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2S)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.0000053 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N1-hydroxy-N4-(3-hydroxypropyl)-N2-[4-(phenylethynyl)benzoyl]-L-aspartamide | |
| 0.00000532 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[3-(2-fluoro-3-methoxyphenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000056 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-([1,1'-biphenyl]-4-yl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.0000058 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-[(4-[[4-([2-[(dimethylamino)methyl]morpholin-4-yl]methyl)phenyl]ethynyl]phenoxy)methyl]-N-hydroxyoxane-4-carboxamide | |
| 0.000006 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide | |
| 0.000006 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-amino-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(phenylethynyl)phenyl]piperazine-1-carboxamide | |
| 0.0000061 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-([4-[(4-methylpiperazin-1-yl)methyl]phenyl]ethynyl)phenoxy]methyl]oxane-4-carboxamide | |
| 0.0000064 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-(6-methoxy-2'-oxo[3,4'-bipyridin]-1'(2'H)-yl)-2-methylbutanamide | |
| 0.0000067 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(3-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | |
| 0.00000675 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[5-(3-fluorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000678 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3'-(propan-2-yl)[1,1'-biphenyl]-4-yl]butanamide | |
| 0.00000681 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[3-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000007 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-([1,1'-biphenyl]-4-yl)-N-[(2S)-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.000007 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-[4-[(4-fluorophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.00000704 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-(2'-methoxy[1,1'-biphenyl]-4-yl)-2-methylbutanamide | |
| 0.0000071 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.0000073 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-1-(hydroxyamino)-3-(methanesulfonyl)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.0000074 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-([[4-(4-chlorophenoxy)phenyl]sulfanyl]methyl)-N-hydroxyoxane-4-carboxamide | |
| 0.0000074 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(1S)-2-(hydroxyamino)-2-oxo-1-phenylethyl]-4-(phenylethynyl)benzamide | |
| 0.0000075 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-([4-[(4-[[4-(propan-2-yl)piperazin-1-yl]methyl]phenyl)ethynyl]phenoxy]methyl)oxane-4-carboxamide | |
| 0.000008 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylpentanamide | |
| 0.000008 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4'-ethyl-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl][1,1'-biphenyl]-4-carboxamide | |
| 0.00000808 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(2,3-difluorophenyl)-1H-1,2,3-triazol-1-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.00000831 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[5-(2-fluorophenyl)-1,2-oxazol-3-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000085 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-oxo-4-phenylpyrimidin-1(6H)-yl)butanamide | |
| 0.0000086 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-methoxy-1-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenoxy]methyl]cyclohexane-1-carboxamide | |
| 0.0000087 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-[[([1,1'-biphenyl]-4-yl)oxy]methyl]-N-hydroxyoxane-4-carboxamide | |
| 0.00000904 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 3-[([1,1'-biphenyl]-4-yl)sulfanyl]-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | |
| 0.00000949 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4'-(3-carbamimidamidopropoxy)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000098 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-1-(hydroxyamino)-3-(methylsulfanyl)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.00001 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[(4-[[4-([[(4-methoxyphenyl)methyl]amino]methyl)phenyl]ethynyl]phenoxy)methyl]oxane-4-carboxamide | |
| 0.00001 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.0000101 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4-(cyclopentyloxy)phenyl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000104 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(trifluoromethyl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | |
| 0.000011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(4-cyclohexyl-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000011 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-(4-[[4-(cyanomethyl)phenyl]ethynyl]phenyl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.0000119 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 3-([1,1'-biphenyl]-4-sulfonyl)-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | |
| 0.000012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-4-[4-(2-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-2-methylbutanamide | |
| 0.000012 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(hydroxymethyl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | |
| 0.000012 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-(1,3-thiazol-5-yl)phenyl]piperazine-1-carboxamide | |
| 0.0000127 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4'-(3-aminopropoxy)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000129 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-[4'-(aminomethyl)[1,1'-biphenyl]-4-yl]-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000013 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-phenylpyridin-2-yl)butanamide | |
| 0.000013 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-2-[5-[([1,1'-biphenyl]-4-yl)ethynyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | |
| 0.0000135 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(1-phenyl-1H-pyrazol-4-yl)butanamide | |
| 0.0000138 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-([1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)butanamide | |
| 0.0000138 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-([1,1'-biphenyl]-4-yl)-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperidine-1-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-[[4-(benzyloxy)phenoxy]methyl]-N-hydroxyoxane-4-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]piperazine-1-carboxamide | |
| 0.000014 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N1-hydroxy-N2-[4-(phenylethynyl)benzoyl]-N4-prop-2-yn-1-yl-L-aspartamide | |
| 0.000015 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(pyridin-2-yl)propanamide | |
| 0.0000163 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4'-(morpholin-4-yl)[1,1'-biphenyl]-4-yl]piperazine-1-carboxamide | |
| 0.000018 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(pyridin-3-yl)propanamide | |
| 0.000021 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(thiophen-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.0000212 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-([4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-4-yl]oxy)butanoic acid | |
| 0.0000216 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-[(pyridin-4-yl)oxy]phenyl]butanamide | |
| 0.000022 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | |
| 0.000022 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylpropanamide | |
| 0.0000221 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[3'-(1H-pyrazol-1-yl)[1,1'-biphenyl]-4-yl]butanamide | |
| 0.0000233 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(4-[[4-(piperazin-1-yl)phenyl]ethynyl]phenyl)piperazine-1-carboxamide | |
| 0.000025 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1-methyl-1H-imidazol-2-yl)propanamide | |
| 0.000026 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-(1-methyl-1H-1,2,3-triazol-5-yl)propanamide | |
| 0.000026 | - |
pH not specified in the publication, 30°C | Escherichia coli | 4-[4-[(4-aminophenyl)ethynyl]phenyl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]piperazine-1-carboxamide | |
| 0.000026 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-1,1-dioxo-4-[4-(phenylethynyl)benzamido]-1lambda6-thiane-4-carboxamide | |
| 0.0000261 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(2'-ethyl[1,1'-biphenyl]-4-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.0000278 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-3-carboxamide | |
| 0.000028 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-5-ethoxy-N,3-dihydroxy-2-methylpentanamide | |
| 0.000028 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2S)-3-amino-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.000029 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-N,3-dihydroxy-2-[1-oxo-5-[4-(phenylethynyl)phenyl]-1,3-dihydro-2H-isoindol-2-yl]butanamide | |
| 0.0000297 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(pyridin-3-yl)phenyl]butanamide | |
| 0.00003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(5-methyl-2-oxo-4-phenylpyridin-1(2H)-yl)butanamide | |
| 0.0000304 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-[4-(phenylsulfanyl)phenyl]butanamide | |
| 0.0000314 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 3-[([1,1'-biphenyl]-4-yl)oxy]-N-hydroxy-2-(methanesulfonyl)-2-methylpropanamide | |
| 0.000033 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-(4-phenylbuta-1,3-diyn-1-yl)phenoxy]methyl]oxane-4-carboxamide | |
| 0.000033 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N1-hydroxy-N4-(2-methoxyethyl)-N2-[4-(phenylethynyl)benzoyl]-L-aspartamide | |
| 0.000035 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-Nalpha-[4-(phenylethynyl)benzoyl]-L-histidinamide | |
| 0.000036 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[4-(phenylethynyl)phenyl]pyrrolidine-1-carboxamide | |
| 0.000039 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo[4,4'-bipyridin]-1(2H)-yl)butanamide | |
| 0.000049 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(6-phenylpyridin-3-yl)butanamide | |
| 0.00005 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-2-[5-([1,1'-biphenyl]-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | |
| 0.000051 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methyl-3-phenylpropanamide | |
| 0.000053 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-4-(2-hydroxy-6-phenylpyridin-3-yl)-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000057 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2-oxo-4-phenylpyrimidin-1(2H)-yl)butanamide | |
| 0.00006 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-N-hydroxy-2-(methanesulfonyl)-2-methyl-4-(2'-oxo[2,4'-bipyridin]-1'(2'H)-yl)butanamide | |
| 0.000063 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyridin-3-yl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.000069 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2R)-4-(4-tert-butyl-2-oxopyridin-1(2H)-yl)-N-hydroxy-2-(methanesulfonyl)-2-methylbutanamide | |
| 0.000072 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2,4-dimethylpentanamide | |
| 0.0000736 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4'-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl][1,1'-biphenyl]-4-carboxylic acid | |
| 0.00008 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(1R)-2-(hydroxyamino)-2-oxo-1-phenylethyl]-4-(phenylethynyl)benzamide | |
| 0.0000825 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzene-1-sulfinyl]methyl]oxane-4-carboxamide | |
| 0.00009 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylheptanamide | |
| 0.000092 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[(4-phenoxyphenoxy)methyl]oxane-4-carboxamide | |
| 0.0000927 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 1-hydroxy-4-[4-[(3R)-4-(hydroxyamino)-3-(methanesulfonyl)-3-methyl-4-oxobutyl]phenoxy]pyridin-1-ium | |
| 0.00012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.000128 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.00013 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-N,3-dihydroxy-2-[1-oxo-5-(phenylethynyl)-1,3-dihydro-2H-isoindol-2-yl]butanamide | |
| 0.000136 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[4-[(pyrazin-2-yl)ethynyl]phenyl]piperazine-1-carboxamide | |
| 0.000139 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[[4-(5-hydroxy-5-methylhexa-1,3-diyn-1-yl)phenoxy]methyl]oxane-4-carboxamide | |
| 0.0001464 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[3-(phenylethynyl)phenyl]pyrrolidine-1-carboxamide | |
| 0.00016 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (2S,3S)-2-[([1,1'-biphenyl]-4-yl)methoxy]-N,3-dihydroxy-2-methylpentanamide | |
| 0.00016 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-methoxy-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0001631 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S)-3-amino-1-(hydroxyamino)-1-oxopropan-2-yl]-4-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | |
| 0.000187 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.00019 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-[(3-methylbut-2-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0002 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-N,3-dihydroxy-2-[3-oxo-6-(phenylethynyl)-1,3-dihydro-2H-indazol-2-yl]butanamide | |
| 0.0002014 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-N2-([[4-(phenylethynyl)phenyl]methyl]carbamoyl)-L-threoninamide | |
| 0.000207 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)piperidine-1-carboxamide | |
| 0.000208 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 1-benzyl-N-hydroxy-4-[4-(phenylethynyl)benzamido]piperidine-4-carboxamide | |
| 0.00025 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[4-[(3-fluorophenyl)methoxy]-3-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.00028 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(4'-propyl[1,1'-biphenyl]-4-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.000286 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[3-hydroxy-1-(hydroxyamino)-2-methyl-1-oxopropan-2-yl][1,1'-biphenyl]-4-carboxamide | |
| 0.000296 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[4-(phenylethynyl)benzamido]thiane-4-carboxamide | |
| 0.0003 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-chloro-5-fluoro-1H-indol-2-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.000334 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[4-(phenylethynyl)benzamido]oxane-4-carboxamide | |
| 0.00035 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[4-[(but-3-en-1-yl)oxy]-3-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0003867 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-3-[4-(phenylethynyl)phenyl]piperidine-1-carboxamide | |
| 0.00039 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 2-[[([1,1'-biphenyl]-4-yl)oxy]methyl]-N,3-dihydroxy-2-methylpropanamide | |
| 0.0005 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-methoxy-3-propyl-5-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0005 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5-methyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperazin-1-yl]ethyl)imidazolidine-2,4-dione | |
| 0.000516 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[2-(hydroxyamino)-2-oxoethyl]-4-(phenylethynyl)benzamide | |
| 0.00056 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-[(3-nitrophenoxy)methyl]phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0006 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5-methyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperidin-1-yl]ethyl)imidazolidine-2,4-dione | |
| 0.0007 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5-ethyl-5-(2-oxo-2-[4-[4-(phenylethynyl)phenyl]piperidin-1-yl]ethyl)imidazolidine-2,4-dione | |
| 0.00084 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.00096 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-fluoro-3-propylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.000971 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-2-[5-[([1,1'-biphenyl]-3-yl)ethynyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl]-N,3-dihydroxybutanamide | |
| 0.0012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-ethoxy-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-fluoro-3-methylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0012689 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-N2-([2-[4-(phenylethynyl)phenyl]ethyl]carbamoyl)-L-threoninamide | |
| 0.0013 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-[(3-nitrophenyl)methoxy]phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0014 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[3-fluoro-4-[(prop-2-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.00154 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-(trifluoromethoxy)benzamide | |
| 0.0016 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(5-fluoro-1H-indol-2-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.002 | - |
pH not specified in the publication, 30°C | Escherichia coli | 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-[(3S)-3-hydroxyhexadecanoyl]-D-glucitol | |
| 0.002067 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[1-(hydroxyamino)-2-methyl-1-oxopropan-2-yl]-4-(phenylethynyl)benzamide | |
| 0.0022 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0027 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-bromophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0033 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[5-fluoro-4-methoxy-2-methyl-3-(prop-2-en-1-yl)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0035 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[1-(hydroxycarbamoyl)cyclohexyl]-4-(phenylethynyl)benzamide | |
| 0.0039 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 4-[(but-3-en-1-yl)oxy]-N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]benzamide | |
| 0.0039445 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-phenylpiperidine-1-carboxamide | |
| 0.0049 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-bromo-4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0049 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[4-(dimethylamino)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0054 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0055 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(1H-indazol-3-yl)-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0055 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(4-iodophenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0056 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[4-[(but-3-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.006 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0072 | - |
pH not specified in the publication, 30°C | Escherichia coli | 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-glucitol | |
| 0.0073 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-butylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0075 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-4-[(prop-2-en-1-yl)oxy]-3-(trifluoromethoxy)benzamide | |
| 0.0078 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0081 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[1-(hydroxycarbamoyl)cyclobutyl]-4-(phenylethynyl)benzamide | |
| 0.0096 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-bromo-5-fluoro-4-methoxyphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0096 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(3-fluoro-4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.01 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(1-butyl-1H-indazol-3-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.01 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[6-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.011 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-4-[4-(phenylethynyl)benzamido]piperidine-4-carboxamide | |
| 0.012 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(2-butyl-2H-indazol-3-yl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.013 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-1H-indazole-3-carboxamide | |
| 0.0178 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-[4-methoxy-3,5-bis(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-thiazole-4-carboxamide | |
| 0.018 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-(4-acetylphenyl)-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0181 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-[(3S)-3-hydroxyhexadecanoyl]-D-glucitol | |
| 0.02 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(4-methylphenyl)-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.0211 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-hydroxy-5,6-dihydro-4H-1,3-oxazine-4-carboxamide | |
| 0.0217 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | N-hydroxy-2-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1,3-thiazole-4-carboxamide | |
| 0.027 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5'-O-[(E)-[(2,3,4-trihydroxyphenyl)methylidene]amino]uridine | |
| 0.03 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5'-O-[(E)-[(3,4-dihydroxyphenyl)methylidene]amino]uridine | |
| 0.0312 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 2-(5-fluoro-1H-indol-2-yl)-N-hydroxy-5,6-dihydro-4H-1,3-oxazine-4-carboxamide | |
| 0.0328 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[3-chloro-4-(trifluoromethoxy)phenyl]-N-hydroxy-4,5-dihydro-1,3-oxazole-4-carboxamide | |
| 0.034 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-N,3-dihydroxy-2-[1-oxo-6-(phenylethynyl)-1,3-dihydro-2H-isoindol-2-yl]butanamide | |
| 0.0385 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-N-hydroxy-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazole-4-carboxamide | |
| 0.041 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S,3R)-N,3-dihydroxy-2-(1-oxo-5-phenyl-1,3-dihydro-2H-isoindol-2-yl)butanamide | |
| 0.0476 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 3-ethoxy-4-fluoro-N-[(2R)-3-hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]benzamide | |
| 0.0587 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | (4R)-2-[4-[(but-3-en-1-yl)oxy]phenyl]-N-hydroxy-4,5-dihydro-1,3-thiazole-4-carboxamide | |
| 0.06 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)benzamide | |
| 0.0625 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 2-(4-fluorophenyl)-N-hydroxy-4,5-dihydro-1,3-thiazole-4-carboxamide | |
| 0.115 | - |
pH not specified in the publication, 30°C | Escherichia coli | 1,5-anhydro-2-deoxy-3-O-hexanoyl-2-[[hydroxy(methyl)phosphoryl]methyl]-D-glucitol | |
| 0.12 | - |
pH not specified in the publication, 30°C | Escherichia coli | 5'-deoxy-5'-[2-([(E)-[(2,3,4-trihydroxyphenyl)methylidene]amino]oxy)acetamido]uridine | |
| 0.192 | - |
pH not specified in the publication, 30°C | Pseudomonas aeruginosa | 1,5-anhydro-2-deoxy-3-O-hexanoyl-2-[[hydroxy(methyl)phosphoryl]methyl]-D-glucitol | |
| 0.48 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | |
| 0.69 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | |
| 2.6 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]propanamide | |
| 10.5 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-2-[[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]methoxy]acetamide | |
| 31.6 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-2-[(1R)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]acetamide | |
| 198 | - |
pH not specified in the publication, 30°C | Escherichia coli | N-hydroxy-2-[(1R)-2-hydroxy-1-[4-([4-[(morpholin-4-yl)methyl]phenyl]ethynyl)phenyl]ethoxy]acetamide | |
| 200 | - |
pH not specified in the publication, 30°C | Escherichia coli | (2S)-N,3-dihydroxy-2-[(1S)-2-hydroxy-1-[4-(phenylethynyl)phenyl]ethoxy]propanamide | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme catalyzes the first committed step of lipid A biosynthesis | Aquifex aeolicus |
| metabolism | the enzyme catalyzes the first committed step of lipid A biosynthesis | Pseudomonas aeruginosa |
| metabolism | the enzyme catalyzes the first committed step of lipid A biosynthesis | Escherichia coli |
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Release 2023.1 (January 2023)
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