Application | Comment | Organism |
---|---|---|
medicine | the enzyme is used for acute lymphoblastic leukemia treatment, the enzyme does not reduces alpha-antiplasmin and plasminogen levels in human patients, overview | Dickeya chrysanthemi |
medicine | the enzyme is used for acute lymphoblastic leukemia treatment, the enzyme reduces alpha-antiplasmin and plasminogen levels in human patients, this together with the elevated level of thrombin activity in the patients lead to an enhanced risk for thrombosis due to delay in fibrin elimination in Escherichia coli L-asparaginase-treated patients, overview | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-asparagine + H2O | Dickeya chrysanthemi | the enzyme does not reduce alpha-antiplasmin and plasminogen levels in human patients with acute lymphoblastic leukemia | L-aspartate + NH3 | - |
? | |
L-asparagine + H2O | Escherichia coli | the enzyme reduces alpha-antiplasmin and plasminogen levels in human patients with acute lymphoblastic leukemia | L-aspartate + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dickeya chrysanthemi | - |
- |
- |
Escherichia coli | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Escherichia coli | - |
commercial preparation | - |
Dickeya chrysanthemi | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-asparagine + H2O | - |
Escherichia coli | L-aspartate + NH3 | - |
? | |
L-asparagine + H2O | - |
Dickeya chrysanthemi | L-aspartate + NH3 | - |
? | |
L-asparagine + H2O | the enzyme does not reduce alpha-antiplasmin and plasminogen levels in human patients with acute lymphoblastic leukemia | Dickeya chrysanthemi | L-aspartate + NH3 | - |
? | |
L-asparagine + H2O | the enzyme reduces alpha-antiplasmin and plasminogen levels in human patients with acute lymphoblastic leukemia | Escherichia coli | L-aspartate + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Erwinase | - |
Dickeya chrysanthemi |
L-asparaginase | - |
Escherichia coli |
L-asparaginase | - |
Dickeya chrysanthemi |