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BRENDA support

Literature summary for 3.4.25.1 extracted from

  • Iqbal, M.; Chatterjee, S.; Kauer, J.C.; Das, M.; Messina, P.; Freed, B.; Biazzo, W.; Siman, R.
    Potent inhibitors of proteasome (1995), J. Med. Chem., 38, 2276-2277.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Thermoplasma acidophilum

Inhibitors

Inhibitors Comment Organism Structure
N-methoxysuccinyl-Glu-Val-Lys-Phe-H modified Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Thermoplasma acidophilum
-
-
-

Reaction

Reaction Comment Organism Reaction ID
cleavage of peptide bonds with very broad specificity mechanism Thermoplasma acidophilum

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-methoxysuccinyl-Glu-Val-Lys-Met-p-nitroanilide + H2O
-
Homo sapiens ?
-
?