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Literature summary for 3.4.24.B4 extracted from

  • Zhang, L.; Yang, M.; Yang, D.; Cavey, G.; Davidson, P.; Gibson, G.
    Molecular interactions of MMP-13 C-terminal domain with chondrocyte proteins (2010), Connect. Tissue Res., 51, 230-239.
    View publication on PubMed
Search for more literature for 3.4.24.B4

Cloned(Commentary)

Cloned (Comment) Organism
HEK-293-EBNA cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 x * 25000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
CTD affinity column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
articular cartilage
-
 Homo sapiens
-
chondrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha2-macroglobulin + H2O
-
 Homo sapiens ?
-
 ?
collagen type VI + H2O
-
 Homo sapiens ?
-
 ?
decorin + H2O
-
 Homo sapiens ?
-
 ?
Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
serglycin + H2O
-
 Homo sapiens ?
-
 ?
syndecan 4 + H2O
-
 Homo sapiens ?
-
 ?
TIMP1 + H2O
-
 Homo sapiens ?
-
 ?
xylosyltransferase 1 + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 25000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MMP-13
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function MMP-13 activity is necessary for normal skeletal development and plays a central role in cartilage degeneration associated with osteoarthritis Homo sapiens