Any feedback?
Literature summary for 3.4.24.B4 extracted from
- p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation (2010), Osteoarthritis Cartilage, 18, 1203-1210.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| MMP-13 real-time PCR expression analysis, overview | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular matrix | - |
Homo sapiens | 31012 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cartilage | from knee or ankle | Homo sapiens | - |
| chondrocyte | articular | Homo sapiens | - |
| additional information | MMP-13 real-time PCR expression analysis, overview | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MMP-13 | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation. Inhibition of both p38alpha and p38gamma with BIRB796 results in less inhibition of MMP-13 production in response to interleukin-1beta or FN-f than does inhibition of only p38alpha with SB203580 | down |
| Homo sapiens | interleukin-1beta and FN-f stimulate MMP-13 expression, dependent on AP-1 activation | up |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
