Literature summary for 3.4.24.B4 extracted from

Julovi, S.M.; Ito, H.; Nishitani, K.; Jackson, C.J.; Nakamura, T.
Hyaluronan inhibits matrix metalloproteinase-13 in human arthritic chondrocytes via CD44 and P38 (2010), J. Orthop. Res., 29, 258-264.

Search for more literature for 3.4.24.B4

Activating Compound

Activating Compound	Comment	Organism	Structure
interleukin-1beta	activates, hyaluronan inhibits interleukin-1beta-stimulated MMP-13 via CD44 in arthritic chondrocytes	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	the enzyme is secreted	Homo sapiens	-	-
intracellular	in cartilage	Homo sapiens	5622	-
additional information	interleukin-1 at 2 ng/ml stimulates the secretion of MMP-13 in both osteoarthritis or rheumatoid arthritis chondrocytes	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cartilage	-	Homo sapiens	-
chondrocyte	arthritic	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-13	-	Homo sapiens

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Release 2023.1 (January 2023)