Cloned (Comment) | Organism |
---|---|
matrix metalloproteinase gene MMP13 and the antiapoptotic genes Birc2, cIAP1, and Birc3, cIAP2, form an amplicon located on chromosome 11q22, and show elevated expression in osteosarcomas | Homo sapiens |
matrix metalloproteinase gene MMP13 and the antiapoptotic genes Birc2, cIAP1, and Birc3, cIAP2, form an amplicon located on chromosome 9A1, and show elevated expression in osteosarcomas | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
C57BL/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
osteosarcoma cell | overexpression of MMP13 | Mus musculus | - |
osteosarcoma cell | overexpression of MMP13 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MMP13 | - |
Mus musculus |
MMP13 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | down-regulation of MMP13, Birc2, or Birc3 results in reduced tumor growth when transplanted into immunodeficient recipient mice, high MMP13 expression enhances osteosarcoma cell survival | Mus musculus |
additional information | down-regulation of MMP13, Birc2, or Birc3 results in reduced tumor growth, while high MMP13 expression enhances osteosarcoma cell survival | Homo sapiens |