Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HIG-82 cell | a synoviocyte cell line | Oryctolagus cuniculus | - |
Synonyms | Comment | Organism |
---|---|---|
MMP-13 | - |
Oryctolagus cuniculus |
Organism | Comment | Expression |
---|---|---|
Oryctolagus cuniculus | 17beta-estadiol reduces the MMP-13 promoter activity | down |
Oryctolagus cuniculus | ER-alpha upregulates MMP-13 expression and acts via an AP-1 regulatory site on the MMP-13 promoter, ER-alpha influences the MMP-13 activity mediated by two separate transcriptional activation domains, AF-1 and AF-2, overview. Both AF-1 and AF-2 domains of ER-alpha are required for regulation of MMP-13 promoter activity | up |