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Literature summary for 3.4.24.B2 extracted from
- Oligopeptidase F (2004), Handbook of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 369-370.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Staphylococcus aureus |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia trachomatis |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma genitalium |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Bacillus subtilis |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus pneumoniae |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus pyogenes |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Staphylococcus epidermidis |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Fusobacterium nucleatum |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Clostridium perfringens |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus agalactiae |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Ureaplasma urealyticum |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Caldicellulosiruptor saccharolyticus |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Streptococcus mutans |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma pneumoniae |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Deinococcus radiodurans |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Listeria monocytogenes |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Borreliella burgdorferi |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Halobacterium sp. |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia muridarum |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Chlamydia pneumoniae |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasma capricolum |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Listeria innocua |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Caldanaerobacter subterraneus subsp. tengcongensis |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Mycoplasmopsis pulmonis |
| additional information | overexpression in Bacillus subtilis inhibits sporulation initiation | Oceanobacillus iheyensis |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in Bacillus subtilis | Bacillus subtilis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | 1 mM inhibits | Lactococcus lactis |  |
| EDTA | 1 mM inhibits, inhibition can be restored with Mn2+ and Co2+ | Lactococcus lactis | |
| NaCl | 0.001 mM decreases enzyme activity by 25% | Lactococcus lactis | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Lactococcus lactis | 5737 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | zinc-binding motif HGXXH | Lactococcus lactis | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
sequence analysis | Lactococcus lactis |
| 90000 | - |
gel filtration | Lactococcus lactis |
| 98000 | - |
gel filtration | Lactococcus lactis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus anthracis | - |
- |
- |
| Bacillus licheniformis | - |
- |
- |
| Bacillus subtilis | - |
- |
- |
| Borreliella burgdorferi | - |
- |
- |
| Caldanaerobacter subterraneus subsp. tengcongensis | - |
- |
- |
| Caldicellulosiruptor saccharolyticus | - |
- |
- |
| Chlamydia muridarum | - |
- |
- |
| Chlamydia pneumoniae | - |
- |
- |
| Chlamydia trachomatis | - |
- |
- |
| Clostridium perfringens | - |
- |
- |
| Deinococcus radiodurans | - |
- |
- |
| Fusobacterium nucleatum | - |
- |
- |
| Halalkalibacterium halodurans | - |
- |
- |
| Halobacterium sp. | - |
- |
- |
| Halobacterium sp. NRC-1 | - |
- |
- |
| Lactococcus lactis | - |
subsp. cremoris NCDO763 and subsp. lactis IL1403 | - |
| Listeria innocua | - |
- |
- |
| Listeria monocytogenes | - |
- |
- |
| Mycoplasma capricolum | - |
- |
- |
| Mycoplasma genitalium | - |
- |
- |
| Mycoplasma pneumoniae | - |
- |
- |
| Mycoplasmopsis pulmonis | - |
- |
- |
| Oceanobacillus iheyensis | - |
- |
- |
| Staphylococcus aureus | - |
- |
- |
| Staphylococcus epidermidis | - |
- |
- |
| Streptococcus agalactiae | - |
- |
- |
| Streptococcus mutans | - |
- |
- |
| Streptococcus pneumoniae | - |
- |
- |
| Streptococcus pyogenes | - |
- |
- |
| Streptococcus thermophilus | - |
- |
- |
| Ureaplasma urealyticum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| by chromatography | Lactococcus lactis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-D-Lys-(2,4-dinitrophenyl) + H2O | - |
Lactococcus lactis | ? | - |
? | |
| bradykinin + H2O | best substrate among peptides | Lactococcus lactis | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Lactococcus lactis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alkaline endopeptidase | - |
Lactococcus lactis |
| LEPI | - |
Lactococcus lactis |
| PepF | - |
Staphylococcus aureus |
| PepF | - |
Chlamydia trachomatis |
| PepF | - |
Mycoplasma genitalium |
| PepF | - |
Bacillus subtilis |
| PepF | - |
Lactococcus lactis |
| PepF | - |
Streptococcus pneumoniae |
| PepF | - |
Streptococcus pyogenes |
| PepF | - |
Staphylococcus epidermidis |
| PepF | - |
Bacillus licheniformis |
| PepF | - |
Streptococcus thermophilus |
| PepF | - |
Fusobacterium nucleatum |
| PepF | - |
Clostridium perfringens |
| PepF | - |
Streptococcus agalactiae |
| PepF | - |
Ureaplasma urealyticum |
| PepF | - |
Caldicellulosiruptor saccharolyticus |
| PepF | - |
Streptococcus mutans |
| PepF | - |
Mycoplasma pneumoniae |
| PepF | - |
Deinococcus radiodurans |
| PepF | - |
Listeria monocytogenes |
| PepF | - |
Borreliella burgdorferi |
| PepF | - |
Halalkalibacterium halodurans |
| PepF | - |
Halobacterium sp. |
| PepF | - |
Chlamydia muridarum |
| PepF | - |
Chlamydia pneumoniae |
| PepF | - |
Bacillus anthracis |
| PepF | - |
Mycoplasma capricolum |
| PepF | - |
Listeria innocua |
| PepF | - |
Caldanaerobacter subterraneus subsp. tengcongensis |
| PepF | - |
Mycoplasmopsis pulmonis |
| PepF | - |
Oceanobacillus iheyensis |
| PepF1 | - |
Lactococcus lactis |
| PepF2 | - |
Lactococcus lactis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Lactococcus lactis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9 | - |
Lactococcus lactis |
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