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Literature summary for 3.4.24.B11 extracted from

  • Gerhardt, S.; Hassall, G.; Hawtin, P.; McCall, E.; Flavell, L.; Minshull, C.; Hargreaves, D.; Ting, A.; Pauptit, R.A.; Parker, A.E.; Abbott, W.M.
    Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains (2007), J. Mol. Biol., 373, 891-902.
    View publication on PubMed
Search for more literature for 3.4.24.B11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf21 insect cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with marimastat, sitting drop vapour diffusion method with 0.2-0.6 M sodium acetate, 0.05 M cadmium sulfate, 0.1 M HEPES (pH 7.0), and 12-22% glycerol Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
marimastat
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ contains a Ca2+-binding site Homo sapiens
Zn2+ zinc metalloproteinase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UHI8
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA Superflow column chromatography, Ni-NTA resin column chromatography, and Superdex 75 gel filtration Homo sapiens

Synonyms

Synonyms Comment Organism
a disintegrin-like and metalloproteinase domain with thrombospondin type I motifs-1
-
 Homo sapiens
ADAMTS-1
-
 Homo sapiens