Literature summary for 3.4.24.B11 extracted from

Lee, N.V.; Rodriguez-Manzaneque, J.C.; Thai, S.N.; Twal, W.O.; Luque, A.; Lyons, K.M.; Argraves, W.S.; Iruela-Arispe, M.L.
Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1 (2005), J. Biol. Chem., 280, 34796-34804.

Search for more literature for 3.4.24.B11

Activating Compound

Activating Compound	Comment	Organism	Structure
fibronectin	2fold enhancement of activity	Homo sapiens
fibulin-1	4fold enhancement of activity with 0.001 mg at 1:1, 1:2, and 1:3 molar ratio in 50 mM Tris, pH 7.4, 10 mM CaCl2, 80 mM NaCl overnight at 37 °C	Homo sapiens

Application

Application	Comment	Organism
medicine	tumor growth inhibitor	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UHI8	-	-

Purification (Commentary)

Purification (Comment)	Organism
CNBr-activated CL-4B-Sepharose affinity chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
aggrecan + H2O	-	Homo sapiens	?	-	?
versican + H2O	-	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
ADAMTS-1	-	Homo sapiens

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Release 2023.1 (January 2023)