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Literature summary for 3.4.24.B10 extracted from

  • Kveiborg, M.; Jacobsen, J.; Lee, M.H.; Nagase, H.; Wewer, U.M.; Murphy, G.
    Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2) (2010), Biochem. J., 430, 79-86.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.B10

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cell Homo sapiens

Protein Variants

Protein Variants Comment Organism
E351Q catalytically inactive Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
N-TIMP-1 N-terminal domain of TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1TACE mutant (V4S/V69L/T98L/TIMP-3-ABloop) of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1[T98L] mutant of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1[TIMP-2-ABloop] mutant of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1[TIMP-3-ABloop] mutant of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1[V4A] mutant of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-1[V4S] mutant of N-TIMP-1, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-2 N-terminal domain of TIMP-2, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-2-deltaABloop mutant of N-TIMP-2, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-2TACE mutant (S2T/A70S/V71L/TIMP-3-ABloop) of N-TIMP-2, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-2TACE[F34G] mutant of N-TIMP-2TACE, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-2TACE[L100E] mutant of N-TIMP-2TACE, tissue inhibitor of metalloproteinase Homo sapiens
N-TIMP-3 N-terminal domain of TIMP-3, tissue inhibitor of metalloproteinase Homo sapiens
TIMP-1 tissue inhibitor of metalloproteinase Homo sapiens
TIMP-2 tissue inhibitor of metalloproteinase Homo sapiens
TIMP-3 tissue inhibitor of metalloproteinase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O43184
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
ADAM12
-
 Homo sapiens
ADAM12-L transmebrane splice variant, full-length protein Homo sapiens
ADAM12-S secreted splice variant Homo sapiens