Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.87 extracted from

  • Hyun, J.; Kim, H.K.; Kim, J.E.; Lim, M.G.; Jung, J.S.; Park, S.; Cho, H.I.
    Correlation between plasma activity of ADAMTS-13 and coagulopathy, and prognosis in disseminated intravascular coagulation (2009), Thromb. Res., 124, 75-79.
    View publication on PubMed
Search for more literature for 3.4.24.87

Application

Application Comment Organism
diagnostics ADAMTS-13 may serve as a diagnostic and prognostic marker of disseminated intravascular coagulation. Patients with a low activity of ADAMTS-13 have a poor survival rate compared to patients with a high activity of ADAMTS-13 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-
intracellular
-
 Homo sapiens 5622
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Homo sapiens
-
additional information ADAMTS-13 levels in healthy controls and patients with disseminated intravascular coagulation Homo sapiens
-
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAMTS13 i.e. a disintegrin-like and metalloprotease with trombospondin type-1 repeats 13 Homo sapiens

General Information

General Information Comment Organism
additional information ADAMTS-13 activity gradually decreases based on the disseminated intravascular coagulation score and D-dimer levels and is correlated with the antithrombin level, representing the consumption of ADAMTS-13 during the ongoing coagulation process. No correlation between ADAMTS-13 activity and neutrophil CD64 expression Homo sapiens