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Literature summary for 3.4.24.87 extracted from

  • Kosugi, N.; Tsurutani, Y.; Isonishi, A.; Hori, Y.; Matsumoto, M.; Fujimura, Y.
    Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor (2010), Intern. Med., 49, 689-693.
    View publication on PubMed
Search for more literature for 3.4.24.87

Inhibitors

Inhibitors Comment Organism Structure
additional information influenza A infection is sufficient to trigger thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens ADAMTS13 specifically cleaves von Willebrand factor multimers at the site of the Tyr1605-Met1606 bond of the VWF-A2 domain von Willebrand factor fragments
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
 Homo sapiens von Willebrand factor fragments
-
 ?
von Willebrand factor + H2O ADAMTS13 specifically cleaves von Willebrand factor multimers at the site of the Tyr1605-Met1606 bond of the VWF-A2 domain Homo sapiens von Willebrand factor fragments
-
 ?

General Information

General Information Comment Organism
additional information Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor, overview Homo sapiens