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BRENDA support

Literature summary for 3.4.24.87 extracted from

  • Bongers, T.N.; de Bruijne, E.L.; Dippel, D.W.; de Jong, A.J.; Deckers, J.W.; Poldermans, D.; de Maat, M.P.; Leebeek, F.W.
    Lower levels of ADAMTS13 are associated with cardiovascular disease in young patients (2009), Atherosclerosis, 207, 250-254.
    View publication on PubMed

Application

Application Comment Organism
medicine levels of ADAMTS13 are lower and levels of Von Willebrand Factor are higher in young patients with cardiovascular disease compared to healthy individuals. Individuals with low levels of ADAMTS13 had five times more risk on cardiovascular disease than subjects with normal levels of ADAMTS13. The relationship is strongest in the subgroup of patients with coronary heart disease. This may be of importance for identifying individuals who are prone to have a cardiovascular event Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q76LX8
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Source Tissue

Source Tissue Comment Organism Textmining
blood plasma levels of ADAMTS13 are lower and levels of von Willebrand Factor are higher in young patients with cardiovascular disease compared to healthy individuals Homo sapiens
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Synonyms

Synonyms Comment Organism
ADAMTS13
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Homo sapiens